Results 301 to 310 of about 502,153 (332)

Structural basis of SARS-CoV-2 polymerase inhibition by nonnucleoside inhibitor HeE1-2Tyr. [PDF]

open access: yesProc Natl Acad Sci U S A
Kabinger F   +5 more
europepmc   +1 more source

Protonated Glutamate and Aspartate Side Chains Can Recognize Phosphodiester Groups via Strong and Short Hydrogen Bonds in Biomacromolecular Complexes

open access: yesAngewandte Chemie International Edition, Accepted Article.
Phosphodiester groups occur ubiquitously in nature, e.g. in nucleic acids or in cyclic (di‐)nucleotides important for signal transduction. Proteins often use polar or positively charged amino acids to interact with the negatively charged phosphodiester groups via hydrogen bonds and salt bridges.
Jens Wöhnert   +5 more
wiley   +1 more source

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