Results 51 to 60 of about 136,691 (332)

Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension

Advanced Science, EarlyView.
H4R and its downstream TRPV1 channel mediate the excitatory effect of TMN histaminergic afferent inputs on GABAergic sympathoinhibitory neurons in RVMM. Intranasal delivery of selective H4R agonist VUF 8430 suppresses renal sympathetic outflow and elicits sustained depressor and bradycardia responses in SHRs and CUMS‐induced hypertensive rats ...
Ying Shi, Yang‐Xun Zhang, Jun‐Yi Chen, Sai Ma, Wei‐Xuan Xue, Wei Li, Qian‐Xiao Li, Bo Song, Ya‐Ting Li, Hong‐Yu Ma, Shu‐Tao Xie, Hong‐Zhao Li, Di‐Jun Chen, Qi‐Peng Zhang, Hui‐Jie Ma, Jian‐Jun Wang, Lei Yu, Xiao‐Yang Zhang, Jing‐Ning Zhu   +18 more
wiley   +1 more source

Anaesthetic management of a child with Wolf–Hirschhorn syndrome

Journal of Clinical and Scientific Research
Wolf–Hirschhorn syndrome (WHS) is a malformation syndrome that is characterised by a partial deletion of the short arm of chromosome 4 and is known to occur in about one per 50,000 births.
Priyanka Das, Shalini Subramanian
doaj   +1 more source

A randomised comparative study to compare the prophylactic use of phenylephrine and norepinephrine in caesarean delivery under spinal anaesthesia

Journal of Obstetric Anaesthesia and Critical Care, 2023
Background: To compare the efficacy and safety of prophylactic intravenous infusions of phenylephrine (0.1 μg/kg/min) and norepinephrine (NE) (0.05 μg/kg/min) for the management of maternal hypotension under spinal anesthesia for cesarean delivery ...
C V Soabir Ali, Jeetendra Kumar Bajaj
doaj   +1 more source

Bradycardia and atrial fibrillation in patients with stable coronary artery disease treated with ivabradine: an analysis from the SIGNIFY study [PDF]

, 2015
Aim: The aim of this study was to determine the impact of emergent bradycardia and atrial fibrillation (AF) on cardiovascular outcomes in 19 083 patients with stable coronary artery disease (CAD) receiving ivabradine or placebo (SIGNIFY, Study assessInG ...
Ferrari, Roberto, Ford, Ian, Fox, Kim, Steg, PPhilippe Gabriel, Tardif, Jean-Claude, Tendera, Michal   +5 more
core   +1 more source

Dengue and Relative Bradycardia

Emerging Infectious Diseases, 2007
To the Editor: We have found that relative bradycardia is a notable clinical feature of dengue fever in Singapore. To our knowledge, this sign has not been previously associated with dengue. Awareness of this possible clinical finding could help in the early recognition of dengue and potentially reduce illness and death associated with dengue virus ...
Paul Ananth Tambyah, Aisha Lateef, Dale A. Fisher   +2 more
openaire   +3 more sources

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

Advanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang, Xinran Ye, Chia‐Kang Ho, Ya Gao, Dongsheng Wen, Jiaming Sun, Yuxin Liu, Yangdan Liu, Guoyuan Wang, Yangbai Sun, Jinyan Zhang, Yifan Zhang, Qingfeng Li   +12 more
wiley   +1 more source

Thermosensitivity of the lobster, Homarus americanus, as determined by cardiac assay [PDF]

, 2000
It is generally accepted that crustaceans detect, and respond to, changes in water temperature, yet few studies have directly addressed their thermosensitivity.
Jury, Steven H., Watson, Winsor H., III
core   +1 more source

Development of a Scoring System to Predict the Treatment Success for Nonoperative Management of Peptic Ulcer Perforation: A Secondary Data Analysis of PPAP Study

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Although surgical treatment is the primary measure for patients with perforated peptic ulcer (PPU), nonoperative management (NOM) has become a common alternative. However, risk score models predicting the success of NOM based on the analysis of a large number of patients remain scarce.
Kei Ito, Akira Endo, Hiromasa Hoshi, Koji Ito, Tomohiro Akutsu, Hikaru Odera, Hideto Shiraki, Takeshi Yokoyama, Yasukazu Narita, Taro Masuda, Akira Suekane, Shigeru Yamagishi, Koji Morishita   +12 more
wiley   +1 more source

Atypical Presentation of Massive Pulmonary Embolism, a Case Report

Archives of Academic Emergency Medicine, 2018
The lack of pathognomonic signs and symptoms makes the diagnosis of pulmonary embolism (PE) difficult. Here, we report a case of a 42-year-old man presented to the emergency department with worsening epigastric pain, hypotension, frank bradycardia, and ...
Alireza Majidi, Sadrollah Mahmoodi, Alireza Baratloo, Sahar Mirbaha   +3 more
doaj   +1 more source

Perioperative and anesthetic deaths: toxicological and medico legal aspects [PDF]

, 2019
Background: Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology.
Argo A., Buscemi R., Karch S. B., Lanzarone A., Roccuzzo R., Zerbo S.   +5 more
core   +1 more source