Bradykinin reduces wound healing in human umbilical vein endothelial cells via downregulation of vascular endothelial growth factor A [PDF]
Journal of InflammationIntroduction Hereditary angioedema (HAE) is characterized by acute swelling attacks triggered by abnormally elevated levels of bradykinin. Despite persistently high bradykinin levels, patients experience only intermittent swelling episodes.
Nevena Dimitrova +8 more
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Bradykinin-activated contractile signalling pathways in human myometrial cells are differentially regulated by arrestin proteins. [PDF]
, 2015 Bradykinin is associated with infections and inflammation, which given the strong correlation between uterine infection and preterm labour may imply that it could play a role in this process.
Craig A. Nash (7644011) +5 more
core +6 more sources
Nature Communications, 2023 An important role for liver in the regulation of adipose tissue thermogenesis upon cold exposure has been suggested; however, the underlying mechanisms remain incompletely defined.
Fei Xiao +14 more
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The des-Arg9-bradykinin/B1R axis: Hepatic damage in COVID-19
Frontiers in Physiology, 2022 Patients infected by the SARS-CoV-2 virus are commonly diagnosed with threatening liver conditions associated with drug-induced therapies and systemic viral action.
Gabriel Moreira de M Mendes +22 more
doaj +1 more source
Bradykinin-induced angioedema in the emergency department
International Journal of Emergency Medicine, 2022 Background Acute airway angioedema commonly occurs through two distinct mechanisms: histamine- and bradykinin-dependent. Although they respond to distinct treatments, these two potentially life-threatening states present similarly.
Jacques Hébert +8 more
doaj +1 more source
Kinin-B2 receptor mediated neuroprotection after NMDA excitotoxicity is reversed in the presence of kinin-B1 receptor agonists. [PDF]
PLoS ONE, 2012 Kinins, with bradykinin and des-Arg(9)-bradykinin being the most important ones, are pro-inflammatory peptides released after tissue injury including stroke.
Antonio H Martins +7 more
doaj +1 more source
Increased plasma bradykinin level is associated with cognitive impairment in Alzheimer's patients
Neurobiology of Disease, 2020 Alzheimer's disease (AD) is characterized by the presence of proteinaceous brain deposits, brain atrophy, vascular dysfunction, and chronic inflammation.
Pradeep K. Singh +4 more
doaj +1 more source
Polymorphisms in the bradykinin B2 receptor gene and childhood asthma [PDF]
, 2001 Bradykinin has been suggested as one of the key mediators of bronchial asthma. Polymorphisms with a potential functional relevance have been described in the B2 bradykinin receptor gene.
Illi, S. +11 more
core +2 more sources
The angiogenic response to Bradykinin "in vitro" : the role of Bradykinin receptors in hypoxic hearts and tumors [PDF]
, 2004 End organ damage resulting from hypertension is a leading cause of morbidity and mortality worldwide. In hypertension, left ventricular mass increases resulting in left ventricular hypertrophy (LVH). LVH increases the risk of heart failure and sudden
Neysari, Shiva
core +1 more source
Pakistan Armed Forces Medical Journal, 2020 Objective: To study the relaxant effect of ropivacaine against acetylcholine and bradykinin induced airway contraction of isolated tracheal tissue of guinea pig in vitro. Study Design: Laboratory based experimental study.
Fatima Qasim Malik +2 more
doaj +4 more sources