Results 131 to 140 of about 1,270,647 (242)

Lung‐Cardiovascular Interactions and Derangements in ARDS

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
This review proposes an anatomical near‐ and far‐field framework for lung‐cardiovascular interactions in ARDS. Grounded in pathological and biological studies, the evidence spans pulmonary vascular, right ventricular, and systemic endothelial derangements and reviews available evidence for targeted therapies.
Pablo A. Sanchez, Connor O'Brien, Matthieu Legrand, Carolyn S. Calfee, Michael A. Matthay   +4 more
wiley   +1 more source

Airway Risk in Angioedema: Validation of a Clinical Triage Algorithm for ENT Referral

Otolaryngology–Head and Neck Surgery, Volume 175, Issue 4, Page 874-880, October 2026.
Abstract Objective To identify clinical factors associated with laryngeal involvement in patients with angioedema and to validate a triage algorithm for determining the need for nasopharyngoscopic evaluation in the emergency department (ED). Study Design A retrospective review was performed of all patients presenting to the ED with angioedema or ...
Dan Yaniv, Igor Vainer, Dean Dudkiewicz, Aviram Mizrachi, Yaniv Hamzani, Eyal Yosefof, Nadav Granat, Gideon Bachar   +7 more
wiley   +1 more source

Effect of icatibant on sweating-induced dermal pain

Journal of Cutaneous Immunology and Allergy
BackgroundExposure to sweating stimuli triggers transient and severe dermal pain in certain individuals. This study aimed to evaluate the analgesic effect of icatibant, a bradykinin B2 receptor antagonist, for the dermal pain induced by sweating stimuli ...
Shunsuke Takahagi, Shunsuke Takahagi, Daiki Matsubara, Emi Murakami, Yumi Aoyama, Shinya Imamura, Atsushi Fukunaga, Atsushi Fukunaga, Yoshiko Oda, Hiroyuki Murota, Michihiro Hide, Michihiro Hide   +11 more
doaj   +1 more source

Involvement of Bradykinin Receptor 2 in Nerve Growth Factor Neuroprotective Activity. [PDF]

Cells, 2020
Petrella C, Ciotti MT, Nisticò R, Piccinin S, Calissano P, Capsoni S, Mercanti D, Cavallaro S, Possenti R, Severini C.   +9 more
europepmc   +1 more source

Bradykinin-induced asthmatic fibroblast/myofibroblast activities via bradykinin B2 receptor and different MAPK pathways

, 2013
Bradykinin drives normal lung fibroblasts into myofibroblasts, induces fibroblast proliferation and activates mitogen activated protein kinase pathways (MAPK) but its effects on bronchial fibroblasts from asthmatics (HBAFb) have not been yet studied.
Fabbri, Leonardo M., Antonino Di Stefano, Anna M. Longo, Petecchia, Loredana, Sabatini, Federica, Alessandra Eva, Fabrizio Luppi, Ricciardolo, Fabio L. M., Sterk, Peter J., Vanni, Cristina, Longo, Anna M., Luppi, Fabrizio, Peter J. Sterk, Eva, Alessandra, Rossi, Giovanni A., Cristina Vanni, Federica Sabatini, Pieter S. Hiemstra, Giovanni A. Rossi, FABBRI, Leonardo, Loredana Petecchia, Stefano, Antonino Di, Hiemstra, Pieter S., Sorbello, Valentina, Valentina Sorbello, Fabio L. M. Ricciardolo   +25 more
core   +1 more source

A Cohort Study on Incidence and Factors Associated With Adverse Drug Reactions of Enalapril in Lusaka, Zambia

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Angiotensin‐converting enzyme inhibitors (ACEIs) are widely prescribed but are associated with adverse drug reactions (ADR), including angioedema, which is typically reported in 0.1%–0.7%. Data from sub‐Saharan Africa are limited. This study aimed to estimate the incidence and risk factors of enalapril‐associated ADRs in a Zambian cohort, with
Ntemena Yikon'a, Ngosa Mumba, Sarah Pedretti, Helen Hoenck, Jonathan Peter, Owen Ngalamika   +5 more
wiley   +1 more source

The lung is more than an organ of gas exchange: immunocompetency, platelets and implications for drug discovery

British Journal of Pharmacology, Volume 183, Issue 20, Page 5999-6006, October 2026.
Abstract The lungs have for a long time been recognised as having pharmacological significance as a specific organ to modulate the pharmacokinetics of endogenous substances needed to maintain homeostasis. The lungs are therefore the site of action of certain drugs that act on these homeostatic processes, resulting in systemic effects on the ...
Simon C. Pitchford
wiley   +1 more source

Estudo dos mecanismos envolvidos nas respostas contráteis induzidas por agonistas B1 e B2 para as cininas em cólons de camundongos: influência da colite induzida por TNBS [PDF]

, 2007
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em FarmacologiaO presente estudo analisou através de técnicas farmacológicas alguns mecanismos envolvidos na resposta contrátil induzida ...
Hara, Daniela Balz
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The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation

International Endodontic Journal, Volume 59, Issue 10, Page 2028-2045, October 2026.
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli, Esteban Ulate, Hugo‐Roberto Munoz, Nestor Ríos‐Osorio   +3 more
wiley   +1 more source

Análise dos mecanismos envolvidos nas respostas contráteis induzidas por agonistas B1 e B2 para as cininas na íris de porco in vitro [PDF]

, 2004
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia.Este trabalho demonstrou que a contração induzida pela BK na íris isolada de porco é mediada pelos receptores B2, com ...
El Sayah, Mariem
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