Results 81 to 90 of about 37,133 (255)

Two Pillars of My Path in Cytopathology: Mentorship From Training to Practice

Diagnostic Cytopathology, EarlyView.
ABSTRACT Mentorship has been a cornerstone of my professional development in cytopathology, shaping both my diagnostic acumen and academic identity. Under the guidance of Dr. Claire Michael during residency and fellowship, I was introduced to a culture of intellectual rigor, systems thinking, and continuous improvement.
Hamza N. Gokozan
wiley   +1 more source

Clinical Characteristics and Treatment Outcomes of 65 Patients With BRAF-Mutated Non-small Cell Lung Cancer

Frontiers in Oncology, 2020
BRAF mutation is an oncogenic driver gene in non-small cell lung cancer (NSCLC) with low frequency. The data of patients with NSCLC harboring BRAF mutations is rare.
Yuxin Mu, Ke Yang, Xuezhi Hao, Yan Wang, Lin Wang, Yutao Liu, Lin Lin, Junling Li, Puyuan Xing   +8 more
doaj   +1 more source

Association of BRAF V600E Mutant Allele Proportion with the Dissemination Stage of Papillary Thyroid Cancer

Biomedicines
The early identification of aggressive forms of cancer is of high importance in treating papillary thyroid cancer (PTC). Disease dissemination is a major factor influencing patient survival. Mutation status of BRAF oncogene, BRAF V600E, is proposed to be
Ivan Blazekovic, Ivan Samija, Josipa Perisa, Koraljka Gall Troselj, Tihana Regovic Dzombeta, Petra Radulovic, Matija Romic, Roko Granic, Ines Sisko Markos, Ana Frobe, Zvonko Kusic, Tomislav Jukic   +11 more
doaj   +1 more source

Real‐world treatment and outcomes of patients with metastatic BRAF mutant colorectal cancer

Cancer Medicine, 2023
Background BRAF mutation occurs in 5%–10% of metastatic colorectal cancers (mCRCs). Patients with BRAF mutant mCRC exhibit a specific metastatic pattern and poor prognosis. Survival outcomes are heterogeneous in cases of mCRC with a BRAF mutation.
Ting Xu, Jian Li, Zhenghang Wang, Xiaotian Zhang, Jun Zhou, Zhihao Lu, Lin Shen, Xicheng Wang   +7 more
doaj   +1 more source

Deceptive Thyroid Pathologies: Anaplastic Thyroid Carcinoma Mimics and Clinical Implications

Head &Neck, EarlyView.
ABSTRACT Background Beyond follicular‐derived thyroid carcinomas, lymphomas, and metastatic disease, there are rare pathologies of the thyroid gland that represent a challenge. We report patients with unusual malignancies that mimic similar aggressive cancers. Methods Retrospective case series.
David Z. Allen, S. Mohsen Hosseini, Mark Zafereo, Miriam Lango, Elizabeth Gardner Grubbs, Priyanka Iyer, Shreyaskumar R. Patel, Vinod Ravi, Naifa Lamki Busaidy, Rui Jennifer Wang, Michelle D. Williams, Maria E. Cabanillas, Anastasios Maniakas   +12 more
wiley   +1 more source

Dramatic response of BRAF V600E-mutant epithelioid glioblastoma to combination therapy with BRAF and MEK inhibitor: establishment and xenograft of a cell line to predict clinical efficacy

Acta Neuropathologica Communications, 2019
Epithelioid glioblastoma is a rare aggressive variant of glioblastoma (GBM) characterized by a dismal prognosis of about 6 months and frequent leptomeningeal dissemination.
Yu Kanemaru, Manabu Natsumeda, Masayasu Okada, Rie Saito, Daiki Kobayashi, Takeyoshi Eda, Jun Watanabe, Shoji Saito, Yoshihiro Tsukamoto, Makoto Oishi, Hirotake Saito, Masayuki Nagahashi, Takahiro Sasaki, Rintaro Hashizume, Hidefumi Aoyama, Toshifumi Wakai, Akiyoshi Kakita, Yukihiko Fujii   +17 more
doaj   +1 more source

The miR-139-5p regulates proliferation of supratentorial paediatric low-grade gliomas by targeting the PI3K/AKT/mTORC1 signalling [PDF]

, 2018
Paediatric low-grade gliomas (pLGGs) are a heterogeneous group of brain tumours associated with a high overall survival: however, they are prone to recur and supratentorial lesions are difficult to resect, being associated with high percentage of disease
Antonelli, Manila, Badiali, Manuela, Besharat, Zein Mersini, Capper, David, Carai, Andrea, Catanzaro, Giuseppina, Chiacchiarini, Martina, Ferretti, Elisabetta, Giangaspero, Felice, Locatelli, Franco, Marras, Carlo Efisio, Mascelli, Samantha, Mastronuzzi, Angela, Miele, Evelina, Po, Agnese, Raso, Alessandro, Schrimpf, Daniel, Stichel, Damian, Tartaglia, Marco, von Deimling, Andreas   +19 more
core   +1 more source

Younger Than 55 Years Old and BRAF V600E Mutation are Risk Factors for Lymph Node Metastasis in Papillary Thyroid Carcinomas ≤1.0 cm but Not in >1.0 cm

International Journal of General Medicine, 2023
Yeqian Lai,1,2 Yihua Gu,1,2 Ming Yu,1,2 Jiaqin Deng1,2 1Department of Thyroid Surgery, Meizhou People’s Hospital, Meizhou Academy of Medical Sciences, Meizhou, People’s Republic of China; 2Guangdong Provincial Key Laboratory of Precision Medicine and ...
Lai Y, Gu Y, Yu M, Deng J
doaj  

Risk factors analysis for BRAF gene V600E mutation in patients with infiltrative follicular papillary thyroid carcinoma [PDF]

精准医学杂志
Objective To investigate the risk factors for BRAF gene V600E mutation in patients with infiltrative follicular papillary thyroid carcinoma (IF-PTC). Methods A total of 134 patients with IF-PTC who underwent surgical treatment in our hospital from August
LI Lei, ZHAN Jiezhi, LI Hui, WANG Ruiqing, ZHAO Cheng
doaj   +1 more source

NRAS Q61R , BRAF V600E immunohistochemistry: a concomitant tool for mutation screening in melanomas [PDF]

, 2014
International audienceThe determination of NRAS and BRAF mutation status is a major requirement in the treatment of patients with metastatic melanoma. Mutation specific antibodies against NRAS(Q61R) and BRAF(V600E) proteins could offer additional data on
Arnaud Uguen, Cédric Le Marechal, Laura Samaison, Laure Paule, Marc De Braekeleer, Matthieu Talagas, Pascale Marcorelles, Sebastian Costa, Zarrin Alavi   +8 more
core   +2 more sources