Results 1 to 10 of about 110,630 (313)
Evaluation of mutations in KRAS and BRAF genes in Iranian population with diffuse gastric cancer [PDF]
World Cancer Research Journal, 2019 OBJECTIVE: RAS proteins control signaling pathways which are the main regulators of the normal cell growth and malignant transformation cells. The point mutations in the KRAS gene are current event in numerous human cancers including pancreatic, lung ...
M. Saneipour, A. Moridnia
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Younger Than 55 Years Old and BRAF V600E Mutation are Risk Factors for Lymph Node Metastasis in Papillary Thyroid Carcinomas ≤1.0 cm but Not in >1.0 cm [PDF]
International Journal of General Medicine, 2023 Yeqian Lai,1,2 Yihua Gu,1,2 Ming Yu,1,2 Jiaqin Deng1,2 1Department of Thyroid Surgery, Meizhou People’s Hospital, Meizhou Academy of Medical Sciences, Meizhou, People’s Republic of China; 2Guangdong Provincial Key Laboratory of Precision Medicine and ...
Lai Y, Gu Y, Yu M, Deng J
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Prevalence of BRAF, NRAS and c-KIT mutations in Slovenian patients with advanced melanoma
Radiology and Oncology, 2018 BRAF, NRAS and c-KIT mutations are characteristics of tumour tissues that influence on treatment decisions in metastatic melanoma patients. Mutation frequency and their correlation with histological characteristics in Slovenian population have not been ...
Moltara Maja Ebert +6 more
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Somatic mutations in colorectal cancer: regional experience
Consilium Medicum, 2022 Introduction. Colorectal cancer is one of the most common malignant neoplasms in economically developed countries, ranking 3rd and 2nd in the structure of morbidity and mortality, respectively. Current knowledge about the molecular features of colorectal
Nikolai A. Ognerubov, Elena N. Ezhova
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The frequency of mutations in advanced thyroid cancer in Japan: a single-center study
Endocrine JournalWe analyzed the outcomes of genetic testing to study the frequency of mutations in advanced thyroid cancer in Japan. Patients (n = 96) with unresectable or metastatic thyroid carcinoma were included for retrospective chart review.
Soji Toda +8 more
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Prognostic value of somatic mutation testing and different methods of treatment of low-risk differentiated thyroid cancer [PDF]
Эндокринная хирургия, 2019 Background: Using molecular testing for prediction the course of the disease could possibly help doctors in making therapeutic decisions about the management of patients, because it remains controversial issues in low-risk differentiated thyroid cancer ...
Vera A. Kachko +2 more
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Сибирский онкологический журнал, 2018 PCR clamping/wild-type blocking PCR with non-extendable locked nucleic acid (LNA) oligonucleotides is used for sensitive detection of somatic mutations in tumors.
V. A. Shamanin +4 more
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Chinese Journal of Lung Cancer, 2021 With the development of precision medicine, therapies of targeting driver genes have significantly prolonged survival in advanced non-small cell lung cancer (NSCLC) patients.
Na LI, Yanjun XU, Yun FAN
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Hyperplastic Polyposis Syndrome Identified with a BRAF Mutation
Gut and Liver, 2012 Background/AimsHydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins) and peroxisome proliferator-activated receptor gamma (PPARγ) ligands can modulate cellular differentiation, proliferation, and apoptosis through various pathways.
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Endocrine ConnectionsNext-generation sequencing (NGS) is of great benefit to clinical practice in terms of identifying genetic alterations. This study aims to clarify the gene background and its influence on thyroid tumors in the Chinese population.
Xu-Feng Chen +6 more
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