Results 11 to 20 of about 5,368 (169)
Molecular genetics of follicular cell thyroid carcinoma
Клиническая и экспериментальная тиреоидология, 2016 Thyroid cancer is the most frequent endocrine malignancy. In the most cases thyroid cancer arises from follicular cells. Diagnosis of the cancer is based on the cytological analysis of fine needle aspiration biopsy of thyroid nodes.
Valentina D. Yakushina +5 more
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Phenotype-Genotype Correlation in Colorectal Cancer: A Real-Life Study
GE: Portuguese Journal of Gastroenterology, 2021 Background and Aims: Colorectal cancer (CRC) is a heterogeneous disease with distinctive genetic pathways, such as chromosomal instability, microsatellite instability and methylator pathway.
Catarina Frias-Gomes +14 more
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BRAF mutation in colorectal cancer: An update [PDF]
Archive of Oncology, 2023 Colon cancer is a leading cause of cancer-related deaths worldwide. About 10% of all colon cancer patients are found to have a mutation in BRAF proto-oncogene that arise as a result of a substitution of amino acid valine with glutamate at position 600 ...
Colombo Alfredo +2 more
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Dabrafenib: A narrative drug review
Cancer Research, Statistics, and Treatment, 2020 Activating mutations in the BRAF gene lead to an unregulated downstream signaling of the MAPK/extracellular-signal-regulated kinase pathway. This pathway is implicated in a range of solid tumors, and BRAF inhibitors are an attractive option in the ...
Lakhan Kashyap +2 more
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Acta Medica Bulgarica, 2021 Introduction: Thyroid carcinoma is the most common endocrine cancer. Some somatic mutations in genes (BRAF, NRAS and TERT) involved in key signaling pathways and genome stability have been recently identified to play an important role in its development.
Vidinov K. +8 more
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Melanoma: clinical-pathological and molecular analysis in patients of Ibague city, Colombia
Duazary, 2020 This study aimed to establish the clinicopathological characteristics of patients with melanoma and its association with BRAF gene mutations. The pathology reports and paraffin-embedded tumor samples from 47 women and 30 men with melanoma, with an ...
Carlos Puentes +5 more
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Türk Patoloji Dergisi, 2023 Objective: Primary anorectal melanomas (AMs) are uncommon neoplasms with aggressive behavior. Molecular profile and clinicopathologic features of AMs are still not well established.
Orhun Cig TASKIN +6 more
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The Ewha Medical Journal, 2021 Over the past decade, substantial advances have been made in the individualization of therapeutic strategies for metastatic colorectal cancer (mCRC).
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Molecular testing approaches in thyroid cancer diagnosis
Journal of Biochemical and Clinical Genetics, 2020 Thyroid cancer (TC) is the most common endocrine malignancy worldwide, with an annual incidence of around 300,000 cases. In recent decades, the incidence of TC in many countries, including Saudi Arabia, has increased significantly.
Abdul-Mohsen Gaeth AlHejaily +1 more
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Cancer Biology & Medicine, 2022 Objective: PD-L1 and PD-L2 expression levels determine immune evasion and the therapeutic efficacy of immune checkpoint blockade. The factors that drive inducible PD-L1 expression have been extensively studied, but mechanisms that result in constitutive ...
Panpan Ma +12 more
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