Results 131 to 140 of about 244,575 (365)

Effect of Training Exercise on Urinary Brain-derived Neurotrophic Factor Levels and Cognitive Performances in Overweight and Obese Subjects [PDF]

open access: bronze, 2016
Angelo Russo   +8 more
openalex   +1 more source

Brain-derived neurotrophic factor: a new adipokine

open access: yesBiomedical Reviews, 2007
Since leptin discovery in 1994, an extensive body of work has been demonstrating that adipose tissue (mainly its white phenotype) expresses not only metabolic, but also endocrine and paracrine phenotypes, particularly in adipobiology of disease. This new biology is achieved predominantly through secretion of adipokines, which include more than hundred ...
Sornelli F   +3 more
openaire   +2 more sources

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

open access: yesAdvanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu   +14 more
wiley   +1 more source

Brain-derived neurotrophic factor derived from sensory neurons plays a critical role in chronic pain

open access: yesBrain : a journal of neurology, 2018
The role of brain-derived neurotrophic factor (BDNF) in pain chronification and neuropathic pain has not been fully determined. Using conditional Bdnf knockout mice, Sikandar et al.
Shafaq Sikandar   +6 more
semanticscholar   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

open access: yesAdvanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian   +5 more
wiley   +1 more source

Microglia overexpressing brain-derived neurotrophic factor promote vascular repair and functional recovery in mice after spinal cord injury

open access: yesNeural Regeneration Research
Spinal cord injury represents a severe form of central nervous system trauma for which effective treatments remain limited. Microglia is the resident immune cells of the central nervous system, play a critical role in spinal cord injury. Previous studies
Fanzhuo Zeng   +8 more
doaj   +1 more source

Dietary fats promote functional and structural changes in the median eminence blood/spinal fluid interface—the protective role for BDNF

open access: yesJournal of Neuroinflammation, 2018
Background The consumption of large amounts of dietary fats activates an inflammatory response in the hypothalamus, damaging key neurons involved in the regulation of caloric intake and energy expenditure.
Albina F. Ramalho   +8 more
doaj   +1 more source

Stingless Bee Honey Improves Spatial Memory in Mice, Probably Associated with Brain-Derived Neurotrophic Factor (BDNF) and Inositol 1,4,5-Triphosphate Receptor Type 1 (Itpr1) Genes [PDF]

open access: hybrid, 2019
Mohd Zulkifli Mustafa   +7 more
openalex   +1 more source

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