Mapping protein–protein interactions by mass spectrometry
Mass Spectrometry Reviews, EarlyView.Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu +4 more
wiley +1 more source
Retinal degeneration driven by brain-derived neurotrophic factor deficiency in microglia and T-lymphocytes. [PDF]
Sci RepReinehr S +9 more
europepmc +1 more source
Intratumoral Nerve Phased Development: A Promising Therapeutic Target
Medicine Bulletin, EarlyView.ABSTRACT The nervous system has emerged as a critical regulator of tumor biology, engaging in dynamic crosstalk with cancer cells. Although the protumorigenic role of innervation is well established, increasing attention is now directed toward reciprocal influences—how tumors actively shape and remodel local nerve networks within the tumor ...
Xiangxian Che +3 more
wiley +1 more source
Function and application of brain‑derived neurotrophic factor precursors (Review). [PDF]
Int J Mol MedChen R +6 more
europepmc +1 more source
Two British women studies replicated the association between the Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) and BMI [PDF]
, 2009 Yin Yao Shugart +11 more
openalex +1 more source
Allogeneic Bone Marrow‐Derived Mesenchymal Stem Cells for Parkinson's Disease: A Randomized Trial
Movement Disorders, EarlyView.Abstract Background Neuroinflammation contributes to Parkinson's disease (PD) progression and motor dysfunction. Allogeneic human mesenchymal stem cells (allo‐hMSCs) may reduce neuroinflammation and improve motor symptoms. Objectives To evaluate the efficacy of repeated intravenous doses of 10 × 106/kg allo‐hMSCs in improving motor symptoms in patients
Mya C. Schiess +15 more
wiley +1 more source
Investigation of the Relationship Between Brain-Derived Neurotrophic Factor and Some Biochemical Parameters in Dairy Cows During the Transition Period. [PDF]
Vet Med Sciİssi M, Ünal CN, Babacan S, Cankara M.
europepmc +1 more source
Vagus Nerve Stimulation in Movement Disorders, from Principles to a Systematic Review of Evidence
Movement Disorders, EarlyView.Abstract Background The vagus nerve (VN), the principal component of the parasympathetic branch of the autonomic nervous system (ANS), mediates bidirec communication between the central nervous system (CNS) and peripheral organs. Vagus nerve stimulation (VNS), delivered through invasive (iVNS) or non‐invasive (transcutaneous cervical [tcVNS] and ...
Francesca Proietti +9 more
wiley +1 more source