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Decreased brain-derived neurotrophic factor expression in chronic kidney disease: integrated clinical and experimental evidence. [PDF]
Chen J +9 more
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Brain Derived Neurotrophic Factor
2014Brain-derived neurotrophic factor (BDNF), is a member of neurotrophin family having roles in survival, growth and function of neurons in the central and peripheral nervous system. BDNF mRNA and protein levels have been identified in the cerebellum, hippocampus, bulbus olfactorius, spinal cord, thalamus, prefrontal cerebral cortex, hypothalamus ...
YARIM, Gül, KAZAK, Filiz
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Progress in Neuro-psychopharmacology and Biological Psychiatry, 2020
BACKGROUND Mood disorders, including major depressive disorder, are among the main causes of disability and early mortality and constitute an important public health problem.
B. Carniel, N. S. da Rocha
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BACKGROUND Mood disorders, including major depressive disorder, are among the main causes of disability and early mortality and constitute an important public health problem.
B. Carniel, N. S. da Rocha
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Brain-derived neurotrophic factor.
Growth factors (Chur, Switzerland), 2005Since the purification of BDNF in 1982, a great deal of evidence has mounted for its central roles in brain development, physiology, and pathology. Aside from its importance in neural development and cell survival, BDNF appears essential to molecular mechanisms of synaptic plasticity.
Devin K, Binder, Helen E, Scharfman
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Brain‐derived neurotrophic factor and post‐stroke depression
Journal of Neuroscience Research, 2019Brain‐derived neurotrophic factor (BDNF) is well known to play a critical role in cognition. Its role in mood disorders, including post stroke depression (PSD), is also recognized with more evidence surfacing. In patients with PSD, their serum BNDF level
Eric T. Zhang, Ping Liao
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Brain-derived neurotrophic factor in multiple sclerosis
Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2019The review presents data on brain-derived neurotrophic factor (BDNF), its structure and functions, the effect on the pathogenesis of experimental autoimmune encephalomyelitis and multiple sclerosis (MS). The correlation of BDNF level with clinical manifestations of MS and the changes of its level during disease-modifying therapy is considered.
A A, Semkina +4 more
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Brain-derived neurotrophic factor in neurodegenerative diseases
Nature Reviews Neurology, 2009Changes in the levels and activities of neurotrophic factors, such as brain-derived neurotrophic factor (BDNF), have been described in a number of neurodegenerative disorders, including Huntington disease, Alzheimer disease and Parkinson disease. It is only in Huntington disease, however, that gain-of-function and loss-of-function experiments have ...
C. Zuccato, E. Cattaneo
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