Design and Rationale of the Cognitive Intervention to Improve Memory in Heart Failure Patients Study [PDF]
, 2018 BACKGROUND: Memory loss is an independent predictor of mortality among heart failure patients. Twenty-three percent to 50% of heart failure patients have comorbid memory loss, but few interventions are available to treat the memory loss.
Dorsey, Susan G. +7 more
core +2 more sources
Correlation Between Irisin and Cognitive Functions in Alzheimer Dementia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The myokine irisin, a recent positive mediator of exercise in the brain, shows neuroprotective functions against Alzheimer's disease (AD). The association between irisin and cognition has never been explored in a biologically defined cohort of patients.
Patrizia Pignataro +12 more
wiley +1 more source
Brain-derived neurotrophic factor associated with kidney function
Diabetology & Metabolic Syndrome, 2023 Background We examined the relationship between brain-derived neurotrophic factor (BDNF) and chronic kidney disease (CKD). Methods First, a cross-sectional study was conducted in 480 participants without known diabetes.
Cheng-Yueh Hsu +2 more
doaj +1 more source
Enhancement of BDNF Concentration and Restoration of the Hypothalamic-Pituitary-Adrenal Axis Accompany Reduced Depressive-Like Behaviour in Stressed Ovariectomised Rats Treated with Either Tualang Honey or Estrogen [PDF]
, 2014 A possible interaction between glucocorticoids and estrogen-induced increases in brain-derived-neurotrophic factor (BDNF) expression in enhancing depressive-like behaviour has been documented.
Ahmad, Asma Hayati +4 more
core +3 more sources
Brain-derived neurotrophic factor released from blood platelets prevents dendritic atrophy of lesioned adult central nervous system neurons [PDF]
, 2023 In humans and other primates, blood platelets contain high concentrations of brain-derived neurotrophic factor due to the expression of the BDNF gene in megakaryocytes.
Barde, Yves-Alain +4 more
core +1 more source
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
Leukemia Inhibitory Factor Augments Neurotrophin Expression and Corticospinal Axon Growth after Adult CNS Injury [PDF]
, 1999 The cytokine leukemia inhibitory factor (LIF) modulates glial and neuronal function in development and after peripheral nerve injury, but little is known regarding its role in the injured adult CNS.
Blesch, A. +5 more
core +1 more source
Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders
Advanced Functional Materials, EarlyView.This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao +5 more
wiley +1 more source
MANF: A New Player in the Control of Energy Homeostasis, and Beyond
Frontiers in Physiology, 2018 All human behaviors, including the control of energy homeostasis, are ultimately mediated by neuronal activities in the brain. Neurotrophic factors represent a protein family that plays important roles in regulating neuronal development, function, and ...
Su Yang, Shihua Li, Xiao-Jiang Li
doaj +1 more source
Brain-derived neurotrophic factor and suicidal behavior [PDF]
QJM, 2010 Studies of the neurobiology of suicidal behavior have become an important and integral part of psychiatric research. Over the past several years, studies of the role of brain-derived neurotrophic factor (BDNF) in the pathophysiology of suicidality have attracted significant interest of researchers. Multiple lines of evidence including studies of levels
openaire +2 more sources