Dynamic changes in DNA methylation of stress-associated genes (OXTR, BDNF) after acute psychosocial stress [PDF]
, 2012 Environmentally induced epigenetic alterations are related to mental health. We investigated quantitative DNA methylation status before and after an acute psychosocial stressor in two stress-related genes: oxytocin receptor (OXTR) and brain-derived ...
Dempster, E. +16 more
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Long-term gene therapy causes transgene-specific changes in the morphology of regenerating retinal ganglion cells [PDF]
, 2012 Recombinant adeno-associated viral (rAAV) vectors can be used to introduce neurotrophic genes into injured CNS neurons, promoting survival and axonal regeneration.
Rodger Jennifer +14 more
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Brain-Derived Neurotrophic Factor in Chronic Periodontitis
Mediators of Inflammation, 2014 Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophic factor family. Outside the nervous system, BDNF has been shown to be expressed in various nonneural tissues, such as periodontal ligament, dental pulp, and odontoblasts.
Jôice Dias Corrêa +8 more
doaj +1 more source
Neural Regeneration Research, 2015 Treatment for optic nerve injury by brain-derived neurotrophic factor or the transplantation of human umbilical cord blood stem cells has gained progress, but analysis by biomechanical indicators is rare.
Zhong-jun Zhang +7 more
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Promoting neurogenesis in hippocampal dentate gyrus of chronic unpredictable stress-induced depressive-like rats with paeoniflorin [PDF]
Journal of Integrative Neuroscience, 2019 Hippocampal neurogenesis plays an important role in the onset and treatment of depressive disorders. Previous studies suggest that paeoniflorin could be used as an antidepressant for treating rats subjected to chronic unpredictable stress. In this study,
Li-Bing Chen, Feng-Mei Qiu, Xiao-Ming Zhong, Cheng Hong, Zhen Huang
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Psychosocial stress experience and DNA methylation in humans - implications for stress-adaptation and -resilience [PDF]
, 2014 : Background: Psychosocial stress, especially early in life, is a risk factor for mental disorders. Recent evidence suggests that stress-related changes in epigenetic patterns, including DNA methylation, could mediate this association. Aim: to examine a
Unternaehrer, Eva
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Brain-derived neurotrophic factor associated with kidney function
Diabetology & Metabolic Syndrome, 2023 Background We examined the relationship between brain-derived neurotrophic factor (BDNF) and chronic kidney disease (CKD). Methods First, a cross-sectional study was conducted in 480 participants without known diabetes.
Cheng-Yueh Hsu +2 more
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Brain-derived neurotrophic factor and its clinical applications
Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2022 Brain-derived neurotrophic factor (BDNF) is a protein found in human beings. This protein is a member of the neurotrophic family of growth factors that relates to the canonical nerve growth factor (NGF). Its main biological process in human is on neurons
Rujittika Mungmunpuntipantip +1 more
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The impact of brain-derived neurotrophic factor gene polymorphisms on post-stroke naming in aphasia.
PLoS ONEPost-stroke aphasia, or language deficits after stroke, afflicts 20-30% of survivors and often persists into the chronic phase. The protein brain-derived neurotrophic factor has been identified as important for neuroplasticity, and is regulated by the ...
Matilda Randighieri +8 more
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MANF: A New Player in the Control of Energy Homeostasis, and Beyond
Frontiers in Physiology, 2018 All human behaviors, including the control of energy homeostasis, are ultimately mediated by neuronal activities in the brain. Neurotrophic factors represent a protein family that plays important roles in regulating neuronal development, function, and ...
Su Yang, Shihua Li, Xiao-Jiang Li
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