Results 11 to 20 of about 101,976 (254)

Brain-derived Neurotrophic Factor in Megakaryocytes [PDF]

Journal of Biological Chemistry, 2016
The biosynthesis of endogenous brain-derived neurotrophic factor (BDNF) has thus far been examined in neurons where it is expressed at very low levels, in an activity-dependent fashion. In humans, BDNF has long been known to accumulate in circulating platelets, at levels far higher than in the brain.
Pedro Chacón-Fernández, Katharina Säuberli, Maria Colzani, Thomas Moreau, Cedric Ghevaert, Yves-Alain Barde   +5 more
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Brain-derived neurotrophic factor in the airways [PDF]

Pharmacology & Therapeutics, 2014
In addition to their well-known roles in the nervous system, there is increasing recognition that neurotrophins such as brain derived neurotrophic factor (BDNF) as well as their receptors are expressed in peripheral tissues including the lung, and can thus potentially contribute to both normal physiology and pathophysiology of several diseases.
Y S, Prakash, Richard J, Martin
openaire   +2 more sources

Acute effects of two different work-to-rest ratio of high-intensity interval training on brain-derived neurotrophic factor in untrained young men

Frontiers in Physiology, 2022
Background: Aerobic exercise could produce a positive effect on the brain by releasing brain-derived neurotrophic factor (BDNF). In untrained healthy humans there seems to be a linear correlation between exercise duration and the positive effect of acute
Kegang Zhao, Zhongyi Hu, Tao Wang, Lei Tian, Maoye Wang, Ruijiang Liu, Chongwen Zuo, Wang Jihua   +7 more
doaj   +1 more source

Assessment of attention, memory, and salivary brain-derived neurotrophic factor in chronic smokers: A cross-sectional observational study

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2023
Objective: Chronic smoking leads to cognitive impairments and affects the peripheral brain-derived neurotrophic factor (BDNF) levels. BDNF is responsible for synaptic plasticity and memory.
A Srividya, A Kannan, C L Krithika, K Yesoda Aniyan   +3 more
doaj   +1 more source

Brain-derived neurotrophic factor and schizophrenia

Psychiatric Genetics, 2019
The brain-derived neurotrophic factor (BDNF) is a secretory growth factor that promotes neuronal proliferation and survival, synaptic plasticity and long-term potentiation in the central nervous system. Brain-derived neurotrophic factor biosynthesis and secretion are chrono-topically regulated processes at the cellular level, accounting for specific ...
Pasquale, Di Carlo, Giovanna, Punzi, Gianluca, Ursini   +2 more
openaire   +3 more sources

Brain-derived neurotrophic factor and schizophrenia [PDF]

Mental Health Clinician, 2016
Abstract Schizophrenia is a severe disorder affecting approximately 1% of the population. Historically, alterations of dopaminergic function were considered the primary cause of schizophrenia. However, for many patients, drugs that alter dopaminergic function do not consistently lead to resolution of the symptoms of schizophrenia.
openaire   +4 more sources

Long noncoding nature brain-derived neurotrophic factor antisense is associated with poor prognosis and functional regulation in non–small cell lung caner

Tumor Biology, 2017
In this study, we evaluated the prognostic potential and functional regulation of human nature antisense, brain-derived neurotrophic factor antisense, in non–small cell lung cancer.
MingJing Shen, Zhonghua Xu, Kanqiu Jiang, Weihua Xu, Yongbin Chen, ZhongHeng Xu   +5 more
doaj   +1 more source

Acute strength exercise and the involvement of small or large muscle mass on plasma brain-derived neurotrophic factor levels

Clinics, 2010
OBJECTIVE: Blood neurotrophins, such as the brain-derived neurotrophic factor, are considered to be of great importance in mediating the benefits of physical exercise.
Paulo Roberto Correia, Aline Pansani, Felipe Machado, Marilia Andrade, Antonio Carlos da Silva, Fulvio Alexandre Scorza, Esper Abrão Cavalheiro, Ricardo Mario Arida   +7 more
doaj   +1 more source

Unaltered low nerve growth factor and high brain-derived neurotrophic factor levels in plasma from patients with fibromyalgia after a 15-week progressive resistance exercise

Journal of Rehabilitation Medicine, 2019
Background: The pathophysiology of fibromyalgia includes central and peripheral factors. Neurotrophins, such as nerve growth factor and brain-derived neurotrophic factor, are involved in peripheral and central nervous system development of pain and ...
Anna Jablochkova, Emmanuel Bäckryd, Eva Kosek, Kaisa Mannerkorpi, Malin Ernberg, Björn Gerdle, Bijar Ghafouri   +6 more
doaj   +1 more source

Repair of peripheral nerve defects with chemically extracted acellular nerve allografts loaded with neurotrophic factors-transfected bone marrow mesenchymal stem cells

Neural Regeneration Research, 2015
Chemically extracted acellular nerve allografts loaded with brain-derived neurotrophic factor-transfected or ciliary neurotrophic factor-transfected bone marrow mesenchymal stem cells have been shown to repair sciatic nerve injury better than chemically ...
Yan-ru Zhang, Ka Ka, Ge-chen Zhang, Hui Zhang, Yan Shang, Guo-qiang Zhao, Wen-hua Huang   +6 more
doaj   +1 more source