Results 21 to 30 of about 180,353 (291)
Abnormal expression of cerebrospinal fluid cation chloride cotransporters in patients with Rett Syndrome [PDF]
, 2013 Objective: Rett Syndrome is a progressive neurodevelopmental disorder caused mainly by mutations in the gene encoding methyl-CpG-binding protein 2. The relevance of MeCP2 for GABAergic function was previously documented in animal models. In these models,
Armstrong, Judith +11 more
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Neural Regeneration Research, 2023 The trigeminal root entry zone is the zone at which the myelination switches from peripheral Schwann cells to central oligodendrocytes. Its special anatomical and physiological structure renders it susceptible to nerve injury.
Madeha Ishag Adam +8 more
doaj +1 more source
Brain-derived neurotrophic factor in the airways [PDF]
Pharmacology & Therapeutics, 2014 In addition to their well-known roles in the nervous system, there is increasing recognition that neurotrophins such as brain derived neurotrophic factor (BDNF) as well as their receptors are expressed in peripheral tissues including the lung, and can thus potentially contribute to both normal physiology and pathophysiology of several diseases.
Y S, Prakash, Richard J, Martin
openaire +2 more sources
Frontiers in Physiology, 2022 Background: Aerobic exercise could produce a positive effect on the brain by releasing brain-derived neurotrophic factor (BDNF). In untrained healthy humans there seems to be a linear correlation between exercise duration and the positive effect of acute
Kegang Zhao +7 more
doaj +1 more source
Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2023 Objective: Chronic smoking leads to cognitive impairments and affects the peripheral brain-derived neurotrophic factor (BDNF) levels. BDNF is responsible for synaptic plasticity and memory.
A Srividya +3 more
doaj +1 more source
Target-derived neurotrophic factors regulate the death of developing forebrain neurons after a change in their trophic requirements [PDF]
, 2001 Many neurons die as the normal brain develops. How this is regulated and whether the mechanism involves neurotrophic molecules from target cells are unknown.
Asavaritikrai, P +3 more
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Brain-derived neurotrophic factor and schizophrenia
Psychiatric Genetics, 2019 The brain-derived neurotrophic factor (BDNF) is a secretory growth factor that promotes neuronal proliferation and survival, synaptic plasticity and long-term potentiation in the central nervous system. Brain-derived neurotrophic factor biosynthesis and secretion are chrono-topically regulated processes at the cellular level, accounting for specific ...
Pasquale, Di Carlo +2 more
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Long-term neuroprotection and neurorestoration by glial cell-derived neurotrophic factor microspheres for the treatment of parkinson's disease [PDF]
, 2011 BACKGROUND: Glial cell-derived neurotrophic factor is a survival factor for dopaminergic neurons and a promising candidate for the treatment of Parkinson's disease. However, the delivery issue of the protein to the brain still remains unsolved.
Ansorena-Artieda, E. (Eduardo) +4 more
core +1 more source
Clinics, 2010 OBJECTIVE: Blood neurotrophins, such as the brain-derived neurotrophic factor, are considered to be of great importance in mediating the benefits of physical exercise.
Paulo Roberto Correia +7 more
doaj +1 more source
Ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons [PDF]
, 1989 Although evidence obtained with the PC12 cell line has suggested a role for the ras oncogene proteins in the signal transduction of nerve growth factor-mediated fiber outgrowth, little is known about the signal transduction mechanisms involved in the ...
Barde, Y. A. +5 more
core +2 more sources