Results 71 to 80 of about 187,908 (321)

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

open access: yesAdvanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni   +15 more
wiley   +1 more source

Expression Analysis of BDNF Gene and BDNF-AS Long Noncoding RNA in Whole Blood Samples of Multiple Sclerosis Patients: Not Always a Negative Correlation between Them

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2018
Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system (CNS), in which axonal damage is a deteriorative factor. Brain-Derived Neurotrophic Factor (BDNF) is described as a neuronal-survival gene, also capable of exerting ...
Vajiheh Gharzi   +5 more
doaj   +1 more source

Progesterone, brain-derived neurotrophic factor and neuroprotection [PDF]

open access: yesNeuroscience, 2013
While the effects of progesterone in the CNS, like those of estrogen, have generally been considered within the context of reproductive function, growing evidence supports its importance in regulating non-reproductive functions including cognition and affect.
M, Singh, C, Su
openaire   +2 more sources

Peptide‐Induced Ferroelectricity in Charge‐Transfer Supramolecular Materials

open access: yesAdvanced Materials, EarlyView.
Bio‐inspired supramolecular charge‐transfer amphiphiles self‐assemble into nanoribbons in water, where peptide chirality‐induced symmetry breaking generates robust ferroelectricity across multiple systems. These water‐processable organic ferroelectrics also enhance neuronal outgrowth and electrophysiological maturity, offering a versatile strategy for ...
James V. Passarelli   +15 more
wiley   +1 more source

Human umbilical cord mesenchymal stem cells promote peripheral nerve repair via paracrine mechanisms

open access: yesNeural Regeneration Research, 2015
Human umbilical cord-derived mesenchymal stem cells (hUCMSCs) represent a promising young-state stem cell source for cell-based therapy. hUCMSC transplantation into the transected sciatic nerve promotes axonal regeneration and functional recovery.
Zhi-yuan Guo   +4 more
doaj   +1 more source

Piezoelectric Stimulation of Neural Cells: Exploring the Synergistic Potential of Hybrid Scaffolds for Enhanced Regeneration

open access: yesAdvanced Materials Interfaces, EarlyView.
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton   +2 more
wiley   +1 more source

The effect of physical exercise on circulating brain‐derived neurotrophic factor in healthy subjects: A meta‐analysis of randomized controlled trials

open access: yesBrain and Behavior, 2022
Objective To investigate how physical exercise (PE) would affect brain‐derived neurotrophic factor (BDNF) in randomized controlled trials (RCTs) of healthy subjects.
Ya‐Hai Wang   +3 more
doaj   +1 more source

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

open access: yesAdvanced Science, EarlyView.
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun   +15 more
wiley   +1 more source

The gut-brain axis, BDNF, NMDA and CNS disorders [PDF]

open access: yes, 2016
Gastro-intestinal (GI) microbiota and the ‘gut-brain axis’ are proving to be increasingly relevant to early brain development and the emergence of psychiatric disorders.
Maqsood, Raeesah, Stone, Trevor W.
core   +1 more source

Human platelets contain brain-derived neurotrophic factor [PDF]

open access: yesThe Journal of Neuroscience, 1990
Neurotrophic support to peripheral sensory neurons is provided by 2 factors of related sequence, NGF and brain-derived neurotrophic factor (BDNF). NGF is present in peripheral target tissues, while BDNF has only been reported in the CNS. We now report the biological characterization and molecular cloning of a cDNA for BDNF from human platelets. BDNF in
H, Yamamoto, M E, Gurney
openaire   +2 more sources

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