Results 71 to 80 of about 249,425 (238)

Brain-derived neurotrophic factor and schizophrenia [PDF]

open access: yesMental Health Clinician, 2016
Abstract Schizophrenia is a severe disorder affecting approximately 1% of the population. Historically, alterations of dopaminergic function were considered the primary cause of schizophrenia. However, for many patients, drugs that alter dopaminergic function do not consistently lead to resolution of the symptoms of schizophrenia.
openaire   +3 more sources

Lactate Mediates the Effects of Exercise on Learning and Memory through SIRT1-Dependent Activation of Hippocampal Brain-Derived Neurotrophic Factor (BDNF)

open access: yesJournal of Neuroscience, 2019
Exercise promotes learning and memory formation. These effects depend on increases in hippocampal BDNF, a growth factor associated with cognitive improvement and the alleviation of depression symptoms.
Lauretta El Hayek   +15 more
semanticscholar   +1 more source

FSD-C10: A more promising novel ROCK inhibitor than Fasudil for treatment of CNS autoimmunity. [PDF]

open access: yes, 2015
Rho-Rho kinase (Rho-ROCK) triggers an intracellular signalling cascade that regulates cell survival, death, adhesion, migration, neurite outgrowth and retraction and influences the generation and development of several neurological disorders.
Chai, Zhi   +12 more
core   +2 more sources

Brain-derived neurotrophic factor in the airways [PDF]

open access: yesPharmacology & Therapeutics, 2014
In addition to their well-known roles in the nervous system, there is increasing recognition that neurotrophins such as brain derived neurotrophic factor (BDNF) as well as their receptors are expressed in peripheral tissues including the lung, and can thus potentially contribute to both normal physiology and pathophysiology of several diseases.
Y S, Prakash, Richard J, Martin
openaire   +2 more sources

Brain-Derived Neurotrophic Factor, Depression, and Physical Activity: Making the Neuroplastic Connection

open access: yesJournal of Neural Transplantation and Plasticity, 2017
Brain-derived neurotrophic factor (BDNF) is a neurotrophin that is vital to the survival, growth, and maintenance of neurons in key brain circuits involved in emotional and cognitive function.
Cristy Phillips
semanticscholar   +1 more source

Expression Analysis of BDNF Gene and BDNF-AS Long Noncoding RNA in Whole Blood Samples of Multiple Sclerosis Patients: Not Always a Negative Correlation between Them

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2018
Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system (CNS), in which axonal damage is a deteriorative factor. Brain-Derived Neurotrophic Factor (BDNF) is described as a neuronal-survival gene, also capable of exerting ...
Vajiheh Gharzi   +5 more
doaj   +1 more source

Depression, Neuroplasticity and Neurotrophic Factors [PDF]

open access: yes, 2009
Depression is a common psychiatric disorder. There is still very little known about the neurobiological alterations that underlie the pathophysiology of depression.
Aslı Sarandöl   +3 more
core  

The gut-brain axis, BDNF, NMDA and CNS disorders [PDF]

open access: yes, 2016
Gastro-intestinal (GI) microbiota and the ‘gut-brain axis’ are proving to be increasingly relevant to early brain development and the emergence of psychiatric disorders.
Maqsood, Raeesah, Stone, Trevor W.
core   +1 more source

Progesterone, brain-derived neurotrophic factor and neuroprotection [PDF]

open access: yesNeuroscience, 2013
While the effects of progesterone in the CNS, like those of estrogen, have generally been considered within the context of reproductive function, growing evidence supports its importance in regulating non-reproductive functions including cognition and affect.
M, Singh, C, Su
openaire   +2 more sources

The Role of Brain-Derived Neurotrophic Factor in Different Psychiatric Disorders and Neurodegenerative Diseases

open access: yesمجله كليه طب الكندي
Brain-derived neurotrophic factor is a widely studied neurotrophins found throughout the mammalian central nervous system. These neurotrophins regulate numerous aspects of neuronal and oligodendroglia development and function, including axonal growth ...
Suzan Hamza   +2 more
doaj   +1 more source

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