Results 71 to 80 of about 92,075 (247)

Combination Therapy With Fingolimod and Neural Stem Cells Promotes Functional Myelination [PDF]

, 2019
Myelination, which occurs predominantly postnatally and continues throughout life, is important for proper neurologic function of the mammalian central nervous system (CNS).
Ciric, Bogoljub, Li, Xing, Lu, Xin-Yu, Ma, Cun-Gen, Rostami, A. M., Ye, Ze-Qin, Zhang, Guang-Xian, Zhang, Yuan   +7 more
core   +1 more source

A polymorphism associated with depressive disorders differentially regulates brain derived neurotrophic factor promoter IV activity [PDF]

, 2012
PMCID: PMC3712170Peer reviewedPublisher ...
Aid, Alasdair MacKenzie, Almeida, Alonso, Alvarez-Buylla, Barrett, Bearden, Bearden, Benjamin Hing, Bernier, Boukhaddaoui, Chen, Chen, Chung, Cornwell, Corvol, Cunha, Davidson, Davidson, De Gobbi, Dijkhuizen, Dixon, Dunham, Dwivedi, Dwivedi, Eriksson, Gaunitz, Gerome Breen, Gould, Hacking, Hamilton, Hansen, Hayashi, He, Heckert, Hedges, Hermann, Hofer, Jaworski, John Quinn, Juhasz, Kauer-Sant'Anna, Kohara, Koppel, Koppel, Korte, Kumar, Kumar, Lettice, Lettice, Liu, Ma, Machado, Machado, MacNicol, Marrisa Lear, Martinez-Aran, Martinowich, Marty, McDowell, Miller, Miller, Murgatroyd, Nielsen, Ovcharenko, Peter McGuffin, Poitras, Pruunsild, Pruunsild, Rockman, Rossi, Sakata, Sanderson, Savitz, Sawada, Scharfman, Scott Davidson, Seale, Shanley, Sharma, Siciliano, Sturm, Sun, Tabuchi, Taliaz, Tao, Tao, Thompson, Tolwani, Weniger, Yan, Yasuda   +91 more
core   +1 more source

Brain-derived neurotrophic factor and suicide pathogenesis [PDF]

Annals of Medicine, 2010
Abstract Suicide is a major public health concern. The etiology and pathogenic mechanisms associated with suicidal behavior are poorly understood. Recent research on the biological perspective of suicide has gained momentum and appears to provide a promising approach for identifying potential risk factors associated with this disorder. One of the areas
openaire   +3 more sources

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

Advanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen   +7 more
wiley   +1 more source

Emerging Therapeutic Strategies for Hearing Loss

Advanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han, Tian Shen, Weiwei He, Hao Wei, Xiaolong Zhao, Wen Yang, Chuan Bu, Xinghua Tang, Yu Zhao, Jiangang Fan   +9 more
wiley   +1 more source

Neurotrophins Role in Depression Neurobiology: A Review of Basic and Clinical Evidence [PDF]

, 2011
Depression is a neuropsychiatric disorder affecting a huge percentage of the active population especially in developed countries. Research has devoted much of its attention to this problematic and many drugs have been developed and are currently ...
Berrocoso Domínguez, Esther María, Borges, Gisela, Micó Segura, Juan Antonio, Neto, Fani L., Torres-Sanchez, Sonia   +4 more
core   +4 more sources

Lecithin Alleviates Memory Deficits and Muscle Attenuation in Chinese Older Adults and SAMP8 Mice

Advanced Science, EarlyView.
This study opens a new avenue for safeguarding cognition and muscle health, averting disability in older age, and treating age‐related pathologies through lecithin supplementation. It serves as a promising nonpharmacological intervention for the crosstalk of muscle and cognition.
Xianyun Wang, Dajun Li, Xiao Ying Li, Weizhao Lu, Huini Ding, Chengyan Qi, Xuan Wang, Jing Shen, Yafei Chi, Tiantian Li, Michelle M. Dunk, Yu An, Hongmei Huang, Kang Yu, Weili Xu, Rong Xiao, Yuandi Xi   +16 more
wiley   +1 more source

Association study of the BDNF gene polymorphism (G196A) with overweight/obesity among women from Northwest of Iran

Egyptian Journal of Medical Human Genetics, 2021
Background Obesity is a health problem defined by surplus body fat accumulation and is one of the leading causes of morbidity and mortality. Earlier studies indicated the influence of brain-derived neurotrophic factor (BDNF) molecular alterations in the ...
Haneieh Honarmand, Mortaza Bonyadi, Abbas Rafat, Reza Mahdavi, Fereshteh Aliasghari   +4 more
doaj   +1 more source

Brain-derived neurotrophic factor in asthmatic children [PDF]

, 2014
Background: Brain-derived neurotrophic factor (BDNF) regulates the cross-talk between the immune and nervous systems which may play an important role in asthma pathophysiology.
Abd Al-Aziz, Manal M, Ibrahim, Maged N, Mostafa, Gehan A, Salama, Ashraf A   +3 more
core   +2 more sources

The Brain Derived Neurotrophic Factor and Personality [PDF]

Advances in Biology, 2014
The study of the biological basis of personality is a timely research endeavor, with the aim of deepening our understanding of human nature. In recent years, a growing body of research has investigated the role of the brain derived neurotrophic factor (BDNF) in the context of individual differences across human beings, with a focus on personality ...
openaire   +2 more sources