Results 141 to 150 of about 7,020,359 (338)

Brain [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1902
openaire   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Brain [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1904
openaire   +4 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Brain Share, Not Brain Drain [PDF]

open access: yesJCO Global Oncology, 2020
Vinay Mathew Thomas, Aju Mathew
openaire   +3 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Localization of extended brain sources from EEG/MEG: The ExSo-MUSIC approach

open access: bronze, 2011
Gwénaël Birot   +3 more
openalex   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

A literacia da leitura em comandos de leitura do livro didáctico de português da 8.ª Classe em Moçambique

open access: yesConfluência
Este trabalho objectiva analisar a abordagem dos comandos de compreensão de leitura do manual de português da 8.ª classe, refletindo em torno da promoção de práticas da literacia da leitura no ensino da Língua Portuguesa em Moçambique.
Brain Daniel Tachiua   +1 more
doaj   +1 more source

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