Results 151 to 160 of about 5,092,170 (312)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Aging and metabolism contribute separately to brain-body health. [PDF]

open access: yesPLoS Biol
Farahani A   +7 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Fluid Flow Measurement in the Mid-1970's

open access: yesMeasurement + Control, 1975
T. J. S. Brain
doaj   +1 more source

HBHL Symposium 2023

open access: yesMcGill Journal of Medicine, 2023
Healthy Brain Healthy Lives, McGill University
doaj   +1 more source

SECmeres outperform extracellular vesicles as potential blood RNA biomarkers for Alzheimer's disease. [PDF]

open access: yesNat Commun
Gonzalez-Kozlova E   +20 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Radiation therapy plus osimertinib <i>vs</i> osimertinib alone in epidermal growth factor receptor mutated non-small cell lung cancer: A systematic review. [PDF]

open access: yesWorld J Methodol
Javed M   +14 more
europepmc   +1 more source

Correspondence of the brain's functional architecture during activation and rest

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2009
Stephen M. Smith   +11 more
semanticscholar   +1 more source

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