Results 71 to 80 of about 8,779,803 (385)

The Gysin Sequence for Quantum Lens Spaces

open access: yes, 2014
We define quantum lens spaces as `direct sums of line bundles' and exhibit them as `total spaces' of certain principal bundles over quantum projective spaces.
Arici, Francesca   +2 more
core   +1 more source

Aging of the Brain [PDF]

open access: yes, 2013
An increasing number of persons live for nine or more decades and enjoy the benefits of a well-functioning brain until the end of their life. In that respect, the cognitive performance in later life and the quality maintenance of the brain are amazing biological phenomena.
Csaba Nyakas   +3 more
openaire   +5 more sources

Liquid brains, solid brains [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2019
Cognitive networks have evolved a broad range of solutions to the problem of gathering, storing and responding to information. Some of these networks are describable as static sets of neurons linked in an adaptive web of connections. These are ‘solid’ networks, with a well-defined and physically persistent architecture. Other systems are formed by sets
Stephanie Forrest   +4 more
openaire   +3 more sources

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm

open access: yesIEEE Transactions on Medical Imaging, 2001
The finite mixture (FM) model is the most commonly used model for statistical segmentation of brain magnetic resonance (MR) images because of its simple mathematical form and the piecewise constant nature of ideal brain MR images.
Yongyue Zhang   +2 more
semanticscholar   +1 more source

Signal transducer and activator of transcription 2 deficiency is a novel disorder of mitochondrial fission [PDF]

open access: yes, 2015
Defects of mitochondrial dynamics are emerging causes of neurological disease. In two children presenting with severe neurological deterioration following viral infection we identified a novel homozygous STAT2 mutation, c.1836C4A (p.Cys612Ter), using ...
Anderson, G   +14 more
core   +1 more source

Bi-allelic GAD1 variants cause a neonatal onset syndromic developmental and epileptic encephalopathy. [PDF]

open access: yes, 2020
Developmental and epileptic encephalopathies are a heterogeneous group of early-onset epilepsy syndromes dramatically impairing neurodevelopment. Modern genomic technologies have revealed a number of monogenic origins and opened the door to therapeutic ...
Alix, E   +30 more
core   +2 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Acknowledgement to Reviewers of Brain Sciences in 2018

open access: yesBrain Sciences, 2019
Rigorous peer-review is the corner-stone of high-quality academic publishing. [...]
Brain Sciences Editorial Office
doaj   +1 more source

Functional connectivity in the resting brain: A network analysis of the default mode hypothesis

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2002
Functional imaging studies have shown that certain brain regions, including posterior cingulate cortex (PCC) and ventral anterior cingulate cortex (vACC), consistently show greater activity during resting states than during cognitive tasks.
M. Greicius   +3 more
semanticscholar   +1 more source

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