Results 21 to 30 of about 793,658 (251)
TMBIM6 enhances dopaminergic neuron survival by modulating the IRE1a pathway in Parkinson’s disease
Cell Death and DiseaseThe core pathological hallmark of Parkinson’s disease (PD) is the progressive degeneration of dopaminergic (DAergic) neurons in the substantia nigra pars compacta (SNpc), driven by misfolding and aggregation of a-synuclein (aSyn) into Lewy bodies.
Pablo Ahumada-Montalva +19 more
doaj +1 more source
Medicina, 2023 Background and Objectives: The inflammatory cells released after intracranial hemorrhage, such as monocytes, macrophages, and neutrophils, activate the inflammatory system. These parameters can be used to evaluate the clinical course of diseases.
Eralp Çevikkalp +1 more
doaj +1 more source
The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review
Pediatric Blood &Cancer, EarlyView.ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo +5 more
wiley +1 more source
Hypopituitarism: A Sequela of Severe Hypoxic Encephalopathy
Journal of the Formosan Medical Association, 2006 Central diabetes insipidus (DI) is an established phenomenon after hypoxic encephalopathy or brain death, but hypopituitarism is seldom described. This study investigated the characteristics of 11 patients with DI and hypopituitarism which developed ...
Deng-Huang Su
doaj +1 more source
Medical Management of Brain-Dead Organ Donors [PDF]
Acute and Critical Care, 2019 With improving healthcare services, the demand for organ transplants has been increasing daily worldwide. Deceased organ donors serve as a good alternative option to meet this demand.
A.S.M. Tanim Anwar, Jae-myeong Lee
doaj +1 more source
Re‐Irradiation in Pediatric Diffuse Midline Glioma: A Multi‐Institutional Retrospective Study
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Children with recurrent diffuse midline gliomas (DMGs) have limited therapeutic options at recurrence. Re‐irradiation (RT2) may be used at progression, but with uncertainty about the benefit. Methods We conducted a multi‐institutional retrospective study of children aged < 18 with DMG treated at three centers (Toronto, Canada ...
Ajay Thomas Alex +13 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background An earlier study on children diagnosed with acute lymphoblastic leukemia (ALL) at Moi Teaching and Referral Hospital (MTRH) in Kenya reported a low event‐free survival (EFS), excess treatment abandonment, and high induction mortality.
Gilbert Olbara +7 more
wiley +1 more source
Brain Death Pregnancy and Dignity: Ethical Issues Between “Brain Death” and the Fetus
PhilosophiesIn this article, we analyze the bioethical issue of brain-dead pregnancy, both from the perspective of its implications for the brain death criterion and with reference to the ethical question of maintaining life support measures for brain-dead pregnant ...
Marco Tuono
doaj +1 more source
Organ Transplant in Brain- Dead Patients from the Perspective of Jurisprudence [PDF]
پژوهشنامه حقوق اسلامی, 2011 The present article analyzes the issue of removing organs from brain dead patients as a matter of fact and as a matter of law. Giving definitions of life and death, it clarifies the position of brain-dead patients.
ehsan ali akbari, nasrollah shamli
doaj +1 more source