Results 61 to 70 of about 4,538,394 (284)

Brain Death: Reconciling Definitions, Criteria, and Tests

open access: yes, 1993
Brain death has been discussed extensively for the last 25 years. Most investigators now believe that requiring death of the entire brain as the criterion for brain death in the Uniform Determination of Death Act and the standard clinical tests of brain
Halevy, Amir, Brody, Baruch
core   +1 more source

Transplantation of the heart after circulatory death of the donor: time for a change in law? [PDF]

open access: yes, 2015
Procurement of organs has always been conducted according to the dead donor rule, that is, after death of the donor — but this practice is being challenged. Introduction Australia has an increasing shortfall in transplantable hearts.
James Tibballs, Neera Bhatia
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Fiftieth anniversary of the first heart transplantation in Switzerland in the context of the worldwide history of heart transplantation

open access: yesSwiss Medical Weekly, 2020
On 3 December 1967, Christiaan Barnard performed the first heart transplantation in the world at Groote Schuur Hospital in Cape Town, South Africa. In the succeeding months, heart transplantations in the USA, Asia and Europe followed. On 14 April 1969,
Markus J. Wilhelm   +5 more
doaj   +1 more source

Diagnosis of Brain Stem Death I

open access: yes, 1982
This third in a series of nine articles on brain death begins a discussion of the practical aspects of diagnosing brain stem death. Pallis, a neurologist, presents guidelines for the physician to use in systematically establishing a diagnosis.
Pallis, Christopher
core   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Legal Status of Brain Death in Japan: Why Many Japanese Do Not Accept "Brain Death" as a Definition of Death

open access: yes, 1993
Several speculations on the reasoning for the lack of performance of organ transplants from brain-dead donors in Japan for the last 8 months since the official acceptance of the recent Final Report will be presented.
Hoshino, Kazumasa
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone   +8 more
wiley   +1 more source

The ABC of Brain Stem Death: The Declaration of Death

open access: yes, 1983
This sixth in a series of nine articles on brain death provides the physician with brief guidelines on when and how to declare that death has occurred.
Pallis, Christopher
core   +1 more source

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