Results 81 to 90 of about 5,759,332 (341)
Possible role of human ribonuclease dicer in the regulation of R loops
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik+2 more
wiley +1 more source
A Thomistic Understanding of Human Death [PDF]
Post-printI will review higher-brain and whole-brain death from the standpoint of Thomas Aquinas’s metaphysical understanding of human nature. I will critique arguments for higher-brain death being a proper interpretation of Aquinas’s views and make a ...
Eberl, Jason T.
core
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei+7 more
wiley +1 more source
Cytochrome P450 oxidoreductase participates in nitric oxide consumption by rat brain [PDF]
In low nanomolar concentrations, NO (nitric oxide) functions as a transmitter in brain and other tissues, whereas near-micromolar NO concentrations are associated with toxicity and cell death.
Garthwaite, J., Hall, C.N., Keynes, R.G.
core +3 more sources
Brain Death in Islamic Jurisprudence
BACKGROUND AND OBJECTIVE: In today's world, Islamic jurisprudence encounters new issues. One of the areas where jurisprudence gets involved is the issues concerned with brain death, whether brain death in jurisprudence and Islamic law is considered the ...
A Nikzad, GA Jorsaraei
doaj
BACKGROUND: Organ donation is considered to be a noble act. Medical and nursing students will be the major healthcare providers in this field in the future.
Britzer Paul Vincent+3 more
doaj +1 more source
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran+3 more
wiley +1 more source
Reply to Melissa Moschella [PDF]
Professor Moschella begins by discussing confusions in the brain death debate surrounding the use of the concepts of “integration” and “wholeness.” Some scholars, she says, such as Alan Shewmon, take the presence of biological integration as an ...
Brugger, E
core +1 more source
Legal dilemmas of maternal brain death: The case of Marlise Muñoz [PDF]
The subject of this article is a case that occurred in Texas in 2013, which has caused great debate between medical and legal professionals, and has stirred public concern.
Drljača Jagoda V.
doaj
Experimental Rat Model for Brain Death Induction and Kidney Transplantation
Background: Experimental animal research has been pivotal in developing clinical kidney transplantation (KTx). One donor-associated risk factor with negative affect of transplantation outcome is brain death (BD).
Majid Esmaeilzadeh+6 more
doaj +1 more source