Results 101 to 110 of about 3,348,173 (330)

Brain food for babies [PDF]

, 2017
How does a mother supply a key building block of the brain required for neurodevelopment to her fetus in pregnancy? The critical requirement of docosahexaenoic acid (DHA) for fetal brain development, and the poor efficiency of its synthesis in humans, is
Freeman, Dilys J., Meyer, Barbara J.
core  

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Impact of prenatal exposure characterization on early risk detection: Methodologic insights for the HEALthy Brain and Child Development (HBCD) study

, 2021
Suena H. Massey, Norrina B. Allen, Lindsay R. Pool, Emily S. Miller, Nicole Pouppirt, Deanna M. Barch, Joan L. Luby, Susan B. Perlman, Cynthia Rogers, Chris Smyser, Lauren S. Wakschlag   +10 more
openalex   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Exploring the usability of the virtual reality module LEAF CAFÉ: a qualitative think-aloud study

BMC Geriatrics
Background The global healthcare system faces increasing strain from our ageing population, primarily due to the growing prevalence of age-related health conditions such as dementia.
Joyce Siette, Christopher Campbell, Patrick J. Adam, Celia B. Harris   +3 more
doaj   +1 more source

Development of a Eudragit-Chitosan Nanosystem for the pH-Dependent Transport of Duloxetine to the Brain: Synthesis, Characterization and In Silico Modeling Analysis

, 2022
Pierre P. D. Kondiah, Sipho Mdanda, Sifiso S. Makhathini, Thankhoe A. Rants’o, Yahya E. Choonara   +4 more
openalex   +2 more sources

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Human infant EEG recordings for 200 object images presented in rapid visual streams

Scientific Data
Understanding the neural basis of human object recognition and semantic knowledge has been a significant area of exploration, with recent focus aiming to reveal the developmental trajectory of this core brain function.
Tijl Grootswagers, Genevieve L. Quek, Zhen Zeng, Manuel Varlet   +3 more
doaj   +1 more source

Increased heterogeneity and task-related reconfiguration of functional connectivity during a lexicosemantic task in autism

NeuroImage: Clinical
Autism spectrum disorder (ASD) is highly heterogeneous in etiology and clinical presentation. Findings on intrinsic functional connectivity (FC) or task-induced FC in ASD have been inconsistent including both over- and underconnectivity and diverse ...
Apeksha Sridhar, R. Joanne Jao Keehn, Molly Wilkinson, Yangfeifei Gao, Michael Olson, Lisa E Mash, Kalekirstos Alemu, Ashley Manley, Ksenija Marinkovic, Ralph-Axel Müller, Annika Linke   +10 more
doaj   +1 more source

Design and development of a deep learning model for brain abnormality detection using MRI

, 2023
Mahesh Pandurang Potadar, Raghunath S. Holambe, R. H. Chile   +2 more
openalex   +1 more source