Results 91 to 100 of about 3,343,469 (285)

A comprehensive EEG dataset for investigating visual touch perception

open access: yesScientific Data
Visual touch perception is fundamental to body awareness and social bonding, helping us perceive ourselves and connect with others. However, understanding its neural basis has been limited by a lack of comprehensive public datasets.
Sophie Smit   +5 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Chronic oral administration of ibrutinib prevents long-term memory deficits and reduces AD pathology and neuroinflammatory responses in a mouse model of AD

open access: yesMolecular Brain
We previously demonstrated that ibrutinib has therapeutic efficacy against AD pathologies when injected intraperitoneally at a lower dosage (10 mg/kg, daily for 2 weeks) or orally at a higher dosage (30 mg/kg, daily for 1 month) in AD mice models ...
Hyun-ju Lee   +9 more
doaj   +1 more source

Exploring the role of brain oscillations in speech perception in noise: Intelligibility of isochronously retimed speech

open access: yesFrontiers in Human Neuroscience, 2016
A growing body of evidence shows that brain oscillations track speech. This mechanism is thought to maximise processing efficiency by allocating resources to important speech information, effectively parsing speech into units of appropriate granularity ...
Vincent Aubanel, Chris Davis, Jeesun Kim
doaj   +1 more source

Brain food for babies [PDF]

open access: yes, 2017
How does a mother supply a key building block of the brain required for neurodevelopment to her fetus in pregnancy? The critical requirement of docosahexaenoic acid (DHA) for fetal brain development, and the poor efficiency of its synthesis in humans, is
Freeman, Dilys J., Meyer, Barbara J.
core  

Monte Carlo simulation of quantum Zeno effect in the brain

open access: yes, 2014
Environmental decoherence appears to be the biggest obstacle for successful construction of quantum mind theories. Nevertheless, the quantum physicist Henry Stapp promoted the view that the mind could utilize quantum Zeno effect to influence brain ...
Georgiev, Danko
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Patterns of neural activity in prelimbic cortex neurons correlate with attentional behavior in the rodent continuous performance test

open access: yesTranslational Psychiatry
Sustained attention, the ability to focus on a stimulus or task over extended periods, is crucial for higher level cognition, and is impaired across multiple neuropsychiatric and neurodevelopmental disorders, including attention-deficit/hyperactivity ...
Jorge Miranda-Barrientos   +7 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Model selection to achieve reproducible associations between resting state EEG features and autism

open access: yesScientific Reports
A concern in the field of autism electroencephalography (EEG) biomarker discovery is their lack of reproducibility. In the present study, we considered the problem of learning reproducible associations between multiple features of resting state (RS ...
William E. Carson   +7 more
doaj   +1 more source

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