Clinical utility of cerebrospinal fluid biomarkers measured by LUMIPULSE® system
Abstract Objectives Cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD) are well‐established in research settings, but their use in routine clinical practice remains a largely unexploited potential. Here, we examined the relationship between CSF biomarkers, measured by a fully automated immunoassay platform, and brain β‐amyloid (Aβ ...
Hisashi Nojima+9 more
wiley +1 more source
Multiple Sclerosis and Seizure Prevalence
Investigators from Oslo University Hospital and other centers in Norway studied changes in the prevalence and incidence of multiple sclerosis (MS) in Vestfold County, Norway, in the period 1983-2003.
J Gordon Millichap, John J Millichap
doaj +1 more source
Background: Posttraumatic stress disorder (PTSD) is prevalent in people with acquired brain injury (ABI). Despite the established efficacy of eye movement desensitization and reprocessing (EMDR) for PTSD in general, evaluation studies on EMDR in ABI ...
E.P.J. Janssen+3 more
doaj +1 more source
Adversarial Learning Based Structural Brain-network Generative Model for Analyzing Mild Cognitive Impairment [PDF]
Mild cognitive impairment(MCI) is a precursor of Alzheimer's disease(AD), and the detection of MCI is of great clinical significance. Analyzing the structural brain networks of patients is vital for the recognition of MCI. However, the current studies on structural brain networks are totally dependent on specific toolboxes, which is time-consuming and ...
arxiv
Effect of lithium on acetylcholine esterase activity, and isozyme pattern in developing chick brain [PDF]
Acetylcholine Esterase is an enzyme, which hydrolyses acetylcholine and is used as a marker for cholinergic neural function. It is known to be involved in synaptogenesis.
Gouri, Ms Anahita+3 more
core
Design and construction of a distributed sensor NET for biotelemetric monitoring of brain energetic metabolism using microsensors and biosensors [PDF]
Neurochemical pathways involved in brain physiology or disease pathogenesis are mostly unknown either in physiological conditions or in neurodegenerative diseases.
Bazzu, Gianfranco+5 more
core +2 more sources
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad+13 more
wiley +1 more source
Clinical heterogeneity in a family with flail arm syndrome and review of hnRNPA1‐related spectrum
Abstract Objective Flail arm syndrome (FAS) is one of the atypical subtypes of amyotrophic lateral sclerosis (ALS). Mutations in hnRNPA1 encoding heterogeneous nuclear ribonucleoprotein (hnRNP) A1 are a rare genetic cause of ALS. Herein, marked clinical heterogeneity of FAS in a pedigree with a known hnRNPA1 variant was described to raise early ...
Xiaochen Han+5 more
wiley +1 more source
Symptoms and Etiologies of Pseudotumor Cerebri
Investigators from Ankara Pediatrics, Turkey, evaluate the clinical symptoms and etiology in records of 53 patients (32 female) diagnosed with pseudotumor cerebri (PTC) in a child neurology department between 2005 and 2012.
J Gordon Millichap, John J Millichap
doaj +1 more source
Posterior reversible encephalopathy syndrome in a woman who used gonadotropin-releasing hormone agonists: a case report [PDF]
Posterior reversible encephalopathy syndrome (PRES) is a newly described adverse effect possibly associated with gonadotropin-releasing hormone (GnRH) agonist therapy.
Minhee Lee+3 more
doaj +1 more source