Results 71 to 80 of about 4,808,098 (303)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reversible brain damage following acute organic solvents' poisoning determined by magnetic resonance [PDF]

Vojnosanitetski Pregled, 2005
Introduction. Acute exposure to the effects of volatile solvents is characterized by the abrupt onset of symptoms and signs of poisoning, and relatively fast recovery in the majority of cases. Case report.
Dujmović Irena, Svetel Marina, Petrović Igor, Stefanova Elka, Koprivšek Katarina, Kozić Duško, Kostić Vladimir S.   +6 more
doaj   +1 more source

Addiction is Not a Brain Disease (and it Matters) [PDF]

Frontiers in Psychiatry, 2013
The claim that addiction is a brain disease is almost universally accepted among scientists who work on addiction. The claim's attraction rests on two grounds: the fact that addiction seems to be characterized by dysfunction in specific neural pathways and the fact that the claim seems to the compassionate response to people who are suffering.
openaire   +3 more sources

brain injury [PDF]

, 2022
Mild Traumatic brain injury (mTBI) is a signature wound in military personnel, and repetitive mTBI has been linked to age‐related neurogenerative disorders that affect white matter (WM) in the brain. However, findings of injury to specific WM tracts have
Velez, Carmen, Mark S. George, Davenport, Nicholas D., Kremen, William S., William S. Kremen, David F. Tate, Williams, M Wright, Adamson, Maheen M., Bouchard, Heather C., Andrei Irimia, Tate, David F., Wilde, Elisabeth A, Shenton, Martha E., Jeremy Elman, Franz, Carol E, Mary R. Newsome, Murray B. Stein, Martha E. Shenton, Shenton, Martha E, Morey, Rajendra A, Tate, David F, Heather C. Bouchard, Michael J. Coleman, Rajendra A. Morey, Sponheim, Scott R., Thompson, Paul M, Coimbra, Raul, Stein, Murray B., Stein, Murray B, Dennis, Emily L., Raul Coimbra, McAllister, Thomas W, Ross D. Zafonte, Delin Sun, Emily L. Dennis, Inga K. Koerte, Scott R. Sponheim, Thomas W. McAllister, Carmen Velez, Newsome, Mary R, Paul M. Thompson, McAllister, Thomas W., Annelise Silva, Bouchard, Heather C, Sun, Delin, Silva, Annelise, Seth G. Disner, Franz, Carol E., Elman, Jeremy, Grant, Gerald, Elbert Geuze, Gerald Grant, Zafonte, Ross D, Williams, M. Wright, Adamson, Maheen M, Lori Shutter, George, Mark S., Shutter, Lori, George, Mark S, Disner, Seth G., Dennis, Emily L, Thompson, Paul M., Davenport, Nicholas D, Disner, Seth G, Carol E. Franz, M. Wright Williams, Maheen M. Adamson, Morey, Rajendra A., Sotiras, Aristeidis, Coleman, Michael J, Sponheim, Scott R, Geuze, Elbert, Koerte, Inga K, Zafonte, Ross D., Elisabeth A. Wilde, Kremen, William S, Nicholas D. Davenport, Aristeidis Sotiras, Koerte, Inga K., Wilde, Elisabeth A., Newsome, Mary R., Irimia, Andrei, Coleman, Michael J.   +82 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Brainstem : neglected locus in neurodegenerative diseases [PDF]

, 2011
The most frequent neurodegenerative diseases (NDs) are Alzheimer’s disease (AD), Parkinson’s disease (PD), and frontotemporal lobar degeneration associated with protein TDP-43 (FTLD–TDP).
Lea Tenenholz Grinberg, Lea T Grinberg, Helmut Heinsen, Udo eRueb, Udo Rueb, Tenenholz Grinberg, Lea, Heinsen, Helmut, Rüb, Udo, Helmut eHeinsen   +8 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Infectious Causes of Encephalitis and Meningoencephalitis in Thailand, 2003–2005

Emerging Infectious Diseases, 2015
Acute encephalitis is a severe neurologic syndrome. Determining etiology from among ≈100 possible agents is difficult. To identify infectious etiologies of encephalitis in Thailand, we conducted surveillance in 7 hospitals during July 2003–August 2005 ...
Sonja J. Olsen, Angela P. Campbell, Krongkaew Supawat, Sahas Liamsuwan, Tawee Chotpitayasunondh, Somsak Laptikulthum, Akravudh Viriyavejakul, Tasanee Tantirittisak, Supoch Tunlayadechanont, Anannit Visudtibhan, Punnee Vasiknanonte, Supachai Janjindamai, Pairoj Boonluksiri, Kiatsak Rajborirug, Veerachai Watanaveeradej, Nino Khetsuriani, Scott F. Dowell   +16 more
doaj   +1 more source