Results 131 to 140 of about 725,765 (358)

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

open access: yesAdvanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt   +2 more
wiley   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

open access: yesAdvanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee   +4 more
wiley   +1 more source

Preclinical Evaluation of a Novel Molecule Targeting Nucleoside Homeostasis to Restore Energy Metabolism and Cognitive Function in Alzheimer's Disease

open access: yesPharmacology Research & Perspectives
Alzheimer's disease (AD) is the most prevalent cause of dementia, characterized by progressive cognitive decline and cerebral metabolic impairment. Yet, the therapeutic options for addressing the disease pathogenesis are limited.
Kuo‐Chen Wu   +7 more
doaj   +1 more source

TEMPERAMENT AS A FACTOR INFLUENCING ON ADAPTIVE RESERVES OF YOUNG SCHOOLCHILDREN ORGANISM

open access: yesВ мире научных открытий, 2017
The aim of the study was to identify the relationship with intensity of energy metabolism and the level of activation of the cerebral cortex in primary schoolchildren with different temperament characteristic and their possible the impact on the backup ...
Natalya Sergeevna Bedereva
doaj   +1 more source

Intersection between metabolic dysfunction, high fat diet consumption, and brain aging [PDF]

open access: yes, 2010
Deleterious neurochemical, structural, and behavioral alterations are a seemingly unavoidable aspect of brain aging. However, the basis for these alterations, as well as the basis for the tremendous variability in regards to the degree to which these ...
Adami   +302 more
core   +1 more source

Expanding the function of oligodendrocytes to brain energy metabolism

open access: yesCurrent Opinion in Neurobiology, 2023
K. Nave, Ebrahim Asadollahi, A. Sasmita
semanticscholar   +1 more source

Generating Cell Surface Nucleated Hydrogels with an Artificial Membrane‐Binding Transglutaminase

open access: yesAdvanced Functional Materials, EarlyView.
Cell‐based therapies require advanced strategies to enhance cell delivery and bioactivity. Cell membrane engineering offers an avenue to impart new functions to delivered cells to boost their viability and function. Here, an artificial membrane‐binding transglutaminase is generated and biophysically characterized.
Rosalia Cuahtecontzi Delint   +6 more
wiley   +1 more source

Brain Energy and Oxygen Metabolism: Emerging Role in Normal Function and Disease

open access: yesFrontiers in Molecular Neuroscience, 2018
Dynamic metabolic changes occurring in neurons are critically important in directing brain plasticity and cognitive function. In other tissue types, disruptions to metabolism and the resultant changes in cellular oxidative state, such as increased ...
M. Watts, R. Pocock, C. Claudianos
semanticscholar   +1 more source

Living Liquid Metal Composites Embedded with Electrogenic Endospores for Next‐Generation Bioelectronics

open access: yesAdvanced Functional Materials, EarlyView.
A new class of living liquid metal composites is introduced, embedding Bacillus subtilis endospores into eutectic gallium–indium (EGaIn). The spores enhance droplet coalescence, strengthen interfacial conductivity, and provide on‐demand electrogenic functionality after germination. The composites exhibit high conductivity, self‐healing, patternability,
Maryam Rezaie, Yang Gao, Seokheun Choi
wiley   +1 more source

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