Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Positive Pharmacological Modulation of Hsp70 in Recovery of Brain Energy Metabolism in Various Models of Cerebral Ischemia [PDF]
И. Ф. Беленичев +4 more
openalex +1 more source
Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt +2 more
wiley +1 more source
ENZYMES OF ENERGY METABOLISM IN BRAIN AND CHRONIC STRESS [PDF]
The development of changes in the activity of creatinkinase, aldolase and succinatdehydrogenase in brain cells under 30-day long stress induced by isolation and violated diurnal cycle has been studied.
Koshoridze N.I. +4 more
doaj
Single-cell imaging tools for brain energy metabolism: a review
. Neurophotonics comes to light at a time in which advances in microscopy and improved calcium reporters are paving the way toward high-resolution functional mapping of the brain. This review relates to a parallel revolution in metabolism.
Alejandro San Martín +18 more
semanticscholar +1 more source
Cre/lox generation of a novel whole-body Kiss1r KO mouse line recapitulates a hypogonadal, obese, and metabolically-impaired phenotype. [PDF]
Kisspeptin and its receptor, Kiss1r, act centrally to stimulate reproduction. Recent evidence indicates that kisspeptin is also important for body weight and metabolism, as whole-body Kiss1r KO mice, developed with gene trap technology, display obesity ...
Kauffman, Alexander S +4 more
core +1 more source
Lipoic acid restores age‐associated impairment of brain energy metabolism through the modulation of
Tianyi Jiang +4 more
openalex +1 more source
A scalable biomimetic platform transforms bioinert poly(ethylene glycol) diacrylate into neuroinstructive matrices via integrating solvent transfer‐induced phase separation, microfluidics, and 3D bioprinting. Bicontinuous, hyperbolically curved microporous networks embedded within a fibrous construct elicit rapid adhesion, robust proliferation, and ...
Prince D. Okoro +8 more
wiley +1 more source
The excitatory neurotransmitter glutamate has been reported to have a major impact on brain energy metabolism. Using primary cultures of rat hippocampal neurons, we observed that glutamate reduces glucose utilization in this cell type, suggesting ...
Fabio eTescarollo +3 more
doaj +1 more source
Correction to: L-Aspartate, L-Ornithine and L-Ornithine-L-Aspartate (LOLA) and Their Impact on Brain Energy Metabolism [PDF]
Abhijit Das +6 more
openalex +1 more source

