Results 191 to 200 of about 710,108 (323)

AI‐Assisted Design and Evaluation of SLM‐Ti64 Implants for Enhanced Bone Regeneration

Advanced Healthcare Materials, EarlyView.
AI‐driven simulations of biological healing, combining biomechanical modeling and machine learning, enable personalized orthopedic treatments. By decoding healing patterns influenced by implants and patient‐specific factors, this approach advances fracture repair understanding, optimizes implant design, and supports precision medicine and sustainable ...
Muhammad Usama Zaheer, Muhammad Hassan Razzaq, Mehmet Fatih Aycan, Yogendra Kumar Mishra   +3 more
wiley   +1 more source

Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk

Advanced Healthcare Materials, EarlyView.
Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor, Giuseppe Longobardi, Or Kandli, Anne Krinsky, Opal Avramoff, Anshika Katyal, Koren Salomon, Adan Miari, Dana Venkert, Tania T. Barnatan, América García Alvarado, Shahar Greenberg, Ronit Satchi‐Fainaro   +12 more
wiley   +1 more source

A Cellular Perspective on Brain Energy Metabolism and Functional Imaging

Neuron, 2015
P. Magistretti, I. Allaman
semanticscholar   +1 more source

Biodegradable Implantable Electronics with Wireless Technology for Real‐Time Clinical Applications

Advanced Healthcare Materials, EarlyView.
The article explores how bioresorbable implantable electronics merge wireless communication and power delivery with biodegradable materials to enable real‐time clinical applications. It highlights advances in materials, system design, and medical uses across neural, cardiovascular, digestive, immune, and drug‐delivery systems.
Myeongki Cho, Jeong Woo Chae, Young‐Jin Park, Ki Jun Yu, Sang Min Won   +4 more
wiley   +1 more source

Brain energy metabolism in intracerebroventricularly administered streptozotocin mouse model of Alzheimer's disease: A ¹H-[¹³C]-NMR study. [PDF]

J Cereb Blood Flow Metab, 2021
Soni ND, Ramesh A, Roy D, Patel AB.
europepmc   +1 more source

Loss of biliverdin reductase‐a (BVR‐A) impairs beneficial effects of CNS insulin on brain energy metabolism favoring the development of Alzheimer's disease (AD) neuropathology

, 2020
Chiara Lanzillotta, Antonella Tramutola, Fabio Di Domenico, Chirag Vasavda, Bindu D. Paul, Solomon H. Snyder, D. Allan Butterfield, Marzia Perluigi, João M. N. Duarte, Eugenio Barone   +9 more
openalex   +2 more sources

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

Specificity of the effects of lead on brain energy metabolism for substrates donating a cytoplasmic reducing equivalent.

, 1975
Richard J. Bull, P M Stanaszek, J. J. O’Neill, S.D. Lutkenhoff   +3 more
openalex   +2 more sources

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

Nature Network Boston, 2020
E. Johnson, E. Dammer, D. Duong, Lingyan Ping, Maotian Zhou, Luming Yin, L. Higginbotham, Andrew Guajardo, Bartholomew White, J. Troncoso, M. Thambisetty, T. Montine, Eddie B. Lee, J. Trojanowski, T. Beach, E. Reiman, V. Haroutunian, Minghui Wang, E. Schadt, Bin Zhang, D. Dickson, Nilufer Ertekin-Taner, T. Golde, V. Petyuk, P. D. De Jager, D. Bennett, T. Wingo, Srikant Rangaraju, I. Hajjar, J. Shulman, J. Lah, A. Levey, N. Seyfried   +32 more
semanticscholar   +1 more source