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The roles of pleiotrophin in brain injuries: a narrative review of the literature [PDF]

open access: yesAnnals of Medicine
Background Pleiotrophin (PTN), a secreted multifunctional growth factor, is highly expressed in the developing brain. Recently, many studies have indicated that PTN participates in the development of brain and plays a neuroprotection after brain injury ...
Yupeng Lei   +4 more
doaj   +2 more sources

Cerebrospinal Fluid and Blood Biomarkers in Patients with Post-Traumatic Disorders of Consciousness: A Scoping Review

open access: yesBrain Sciences, 2023
(1) Background: Cerebrospinal fluid (CSF) and blood biomarkers are emerging tools used to obtain information on secondary brain damage and to improve diagnostic and prognostic accuracy for patients with prolonged post-traumatic disorders of consciousness
Sergio Bagnato, Cristina Boccagni
doaj   +1 more source

Lumbosacral Sagittal Alignment in Association to Intervertebral Disc Diseases [PDF]

open access: yesAsian Spine Journal, 2014
Study DesignA cross-sectional case-control study was designed to compare the sagittal alignment of lumbosacral regions in two groups of patients suffering from low back pain, one with intervertebral disc pathologies and one without.PurposeTo evaluate the
Zohreh Habibi   +4 more
doaj   +1 more source

ROBOCOP (ROBOtic Care of Poststroke Pain): Study Protocol for a Randomized Trial to Assess Robot-Assisted Functional and Motor Recovery and Impact on Poststroke Pain Development

open access: yesFrontiers in Neurology, 2022
BackgroundStroke is one of the most frequent causes of death and disability worldwide. It is accompanied by the impaired motor function of the upper extremities in over 69% of patients up to hemiplegia in the following 5 years in 56% of cases.
Loris Pignolo   +5 more
doaj   +1 more source

Biomarkers of Brain Injury: A Window on Mechanisms of Injury and Recovery in the Brain

open access: yesBrain Sciences, 2022
The decision-making process regarding management after severe acute brain injury is based on clinical evaluation and depends on the injury etiology as well as radiological and neurophysiological data [...]
Sergio Bagnato
doaj   +1 more source

Serum BDNF Levels Are Reduced in Patients with Disorders of Consciousness and Are Not Modified by Verticalization with Robot-Assisted Lower-Limb Training

open access: yesNeural Plasticity, 2020
Little is known about plastic changes occurring in the brains of patients with severe disorders of consciousness (DOCs) caused by acute brain injuries at rest and during rehabilitative treatment. Brain-derived neurotrophic factor (BDNF) is a neurotrophin
Sergio Bagnato   +7 more
doaj   +1 more source

Sustained Axonal Degeneration in Prolonged Disorders of Consciousness

open access: yesBrain Sciences, 2021
(1) Background: Sustained axonal degeneration may play a critical role in prolonged disorder of consciousness (DOCs) pathophysiology. We evaluated levels of neurofilament light chain (NFL), an axonal injury marker, in patients with unresponsive ...
Sergio Bagnato   +14 more
doaj   +1 more source

Effectiveness of training with motion-controlled commercial video games for hand and arm function in people with cerebral palsy: A systematic review and meta-analysis

open access: yesJournal of Rehabilitation Medicine, 2020
Objective: To examine the effect of motion-controlled commercial video games compared with traditional occupational and physiotherapy methods for hand and arm function in persons of all ages with cerebral palsy.
Truls Johansen   +3 more
doaj   +1 more source

Investigating microRNAs as biomarkers in disorders of consciousness: a longitudinal multicenter study

open access: yesScientific Reports, 2023
MicroRNAs (miRNAs) are involved in gene regulation and may affect secondary brain injury and recovery in patients with disorders of consciousness (DoC).
Nicolò Musso   +14 more
doaj   +1 more source

Visualizing traumatic brain injuries

open access: yeseLife, 2021
Zebrafish larvae models can be used to study the link between seizures and the neurodegeneration that follows brain trauma.
Marc Ekker
doaj   +1 more source

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