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The roles of pleiotrophin in brain injuries: a narrative review of the literature [PDF]
Background Pleiotrophin (PTN), a secreted multifunctional growth factor, is highly expressed in the developing brain. Recently, many studies have indicated that PTN participates in the development of brain and plays a neuroprotection after brain injury ...
Yupeng Lei +4 more
doaj +2 more sources
Animal models have played a critical role in elucidating the complex pathogenesis of traumatic brain injury, the major cause of death and disability in young adults in Western countries. This review discusses how different types of animal models are useful for the study of neuropathologic processes in traumatic, blunt, nonmissile head injury.
Finnie, J., Blumbergs, P.
+8 more sources
(1) Background: Cerebrospinal fluid (CSF) and blood biomarkers are emerging tools used to obtain information on secondary brain damage and to improve diagnostic and prognostic accuracy for patients with prolonged post-traumatic disorders of consciousness
Sergio Bagnato, Cristina Boccagni
doaj +1 more source
Lumbosacral Sagittal Alignment in Association to Intervertebral Disc Diseases [PDF]
Study DesignA cross-sectional case-control study was designed to compare the sagittal alignment of lumbosacral regions in two groups of patients suffering from low back pain, one with intervertebral disc pathologies and one without.PurposeTo evaluate the
Zohreh Habibi +4 more
doaj +1 more source
There is an increasing incidence of military traumatic brain injury (TBI), and similar injuries are seen in civilians in war zones or terrorist incidents. Indeed, blast-induced mild TBI has been referred to as the signature injury of the conflicts in Iraq and Afghanistan.
Jane E, Risdall, David K, Menon
openaire +4 more sources
BackgroundStroke is one of the most frequent causes of death and disability worldwide. It is accompanied by the impaired motor function of the upper extremities in over 69% of patients up to hemiplegia in the following 5 years in 56% of cases.
Loris Pignolo +5 more
doaj +1 more source
Biomarkers of Brain Injury: A Window on Mechanisms of Injury and Recovery in the Brain
The decision-making process regarding management after severe acute brain injury is based on clinical evaluation and depends on the injury etiology as well as radiological and neurophysiological data [...]
Sergio Bagnato
doaj +1 more source
Little is known about plastic changes occurring in the brains of patients with severe disorders of consciousness (DOCs) caused by acute brain injuries at rest and during rehabilitative treatment. Brain-derived neurotrophic factor (BDNF) is a neurotrophin
Sergio Bagnato +7 more
doaj +1 more source
Mild traumatic brain injury (mTBI), commonly known as concussion, is one of the most common neurologic disorders [1]. Based on emergency room visits, hospitalizations, and deaths, an estimated 1.7 million people sustain a traumatic brain injury (TBI) annually in the United States [2]. About 80% of TBIs that occur each year are mild TBI [3].
Greenwald, Brian D. +2 more
openaire +2 more sources
Sports-related brain injury in the general population: An epidemiological study [PDF]
Objectives To determine the incidence, nature and severity of all sports-related brain injuries in the general population. Design Population-based epidemiological incidence study.
Dowell, Tony +6 more
core +2 more sources

