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Animal models have played a critical role in elucidating the complex pathogenesis of traumatic brain injury, the major cause of death and disability in young adults in Western countries. This review discusses how different types of animal models are useful for the study of neuropathologic processes in traumatic, blunt, nonmissile head injury.
Finnie, J., Blumbergs, P.
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There is an increasing incidence of military traumatic brain injury (TBI), and similar injuries are seen in civilians in war zones or terrorist incidents. Indeed, blast-induced mild TBI has been referred to as the signature injury of the conflicts in Iraq and Afghanistan.
Jane E, Risdall, David K, Menon
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In the article “A Prospective Diffusion Tensor Imaging Study in Mild Traumatic Brain Injury” ( Neurology ® 2010;74:643–650), Andrew Mayer and colleagues studied the effects of mild brain injury using a special kind of magnetic resonance image (MRI). The new MRI sequence is called diffusion tensor imaging (DTI).
Emily, Gilmore, Steven, Karceski
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Traumatic brain injuries [PDF]
Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe. Mild TBI (the least severe form) is synonymous with concussion and is typically caused by blunt non-penetrating head trauma. The trauma causes stretching and tearing of axons, which leads to diffuse axonal injury - the best-studied pathogenetic mechanism of ...
Blennow, K +7 more
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A head trauma is any injury that results in trauma to the skull, scalp, or brain. Every patient with a suspected head trauma should initially undergo a focused neurological examination which consists of the Glasgow Coma Scale Score (GCS), plus pupillary reactivity, that classifies the traumatic brain injury (TBI) as mild, moderate, or severe.
Julian E. Bailes, Cesar V. Borlongan
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Postconcussion Syndrome / Disorder or Mild Traumatic Brain Injury: diagnostic issues and treatment
Traumatic brain injury at the milder end of the spectrum is far more common than the moderate-severe spectrum. Mild traumatic injury (mTBI) accounts for approximately 80% of traumatic brain injuries [1].
Daniel Freedland
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Neurological consequences of traumatic brain injuries in sports. [PDF]
Traumatic brain injury (TBI) is common in boxing and other contact sports. The long term irreversible and progressive aftermath of TBI in boxers depicted as punch drunk syndrome was described almost a century ago and is now widely referred as chronic ...
Hardy, J, Ling, H, Zetterberg, H
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Complex forensic medical evaluation of the traumatic brain injury: case of practice
The problem of studying the mechanisms of the occurrence of traumatic brain injury remains a very urgent issue for forensic medicine. The high incidence and high mortality rate of head injuries underlines its importance to experts. The article presents a
Svіtlana Diachenko +3 more
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Mechanisms of Mitochondrial Oxidative Stress in Brain Injury: From Pathophysiology to Therapeutics
Mitochondrial oxidative stress has been implicated in various forms of brain injury, both traumatic and non-traumatic. Due to its oxidative demand, the brain is intimately dependent on its mitochondrial functioning.
Andrew Nguyen +4 more
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Objectives: Sport-related traumatic brain injuries are a significant public health burden, with hundreds of thousands sustained annually in North America.
Adriana M Workewych +5 more
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