Results 21 to 30 of about 91,468 (256)

Traumatic brain injury

The Lancet, 2000
The decrease in mortality and improved outcome for patients with severe traumatic brain injury over the past 25 years can be attributed to the approach of "squeezing oxygenated blood through a swollen brain". Quantification of cerebral perfusion by monitoring of intracranial pressure and treatment of cerebral hypoperfusion decrease secondary injury ...
openaire   +2 more sources

C-reactive protein to albumin ratio and Glasgow Coma Scale score as the predictors for weaning outcomes in traumatic brain injury

Annals of Medicine
Objective To identify the prognostic value of C-reactive protein to albumin ratio (CRP/ALB, CAR) and Glasgow Coma Scale (GCS) score in the weaning outcomes of mechanical ventilation (MV) in patients with traumatic brain injury (TBI).Methods Medical ...
Jiaxuan Zeng, Jiazhuo Liu, Yin Lu, Jiahui Fu, Dong Han, Jiali Chen, Zhimin Zou, Qin Li, Kun Zhang, Hongping Tan, Wenzhong Yu, Xiucai Wei, Zhengtao Gu, Li Li   +13 more
doaj   +1 more source

Clinical profile, management, and outcome of pediatric neurotrauma: a multicentric observational study [PDF]

Journal of Trauma and Injury
Purpose Pediatric neurotrauma (pNT) includes pediatric traumatic brain injury and spinal cord injury. The incidence and distribution of pNT by age and sex remain understudied, with several gaps in both epidemiological and clinical data.
Sanat Kumar Khanna, Anil Kumar, Anand Kumar Katiyar, Kundan Mishra   +3 more
doaj   +1 more source

Flexor tenotomies for the treatment of bilateral wrist contracture after traumatic brain injury: A case report

Clinical Case Reports, 2023
Key Clinical Message Traumatic brain injuries have the potential to cause the development of long‐term complications. We aim to show that the use of flexor tenotomies in the treatment of flexion contractures following traumatic brain injury is a viable ...
Elizabeth Brown, Tyler Kastner, Justin Harder, Cameron Cox, Brendan MacKay   +4 more
doaj   +1 more source

Tau as a fluid biomarker of concussion and neurodegeneration

Concussion, 2022
Concussion is predominant among the vast number of traumatic brain injuries that occur worldwide. Difficulties in timely identification, whether concussion led to neuronal injury or not, diagnosis and the lack of prognostic tools for adequate management ...
Iftakher Hossain, Kaj Blennow, Jussi P Posti, Henrik Zetterberg   +3 more
doaj   +1 more source

Change in Mental Health and Resilience in Childhood Cancer Survivors After Attending a Person‐Centred State‐of‐the‐Art Late Effects Clinic—on Behalf of the PanCareFollowUp Consortium

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Person‐centred follow‐up care based on evidence‐based clinical practice guidelines and providing individualised information should help to inform and reassure survivors about their medical and psychosocial situation and provide treatment and support where needed.
Gisela Michel, Mieke Rijken, Marietta Kokla, Charlotte Sleurs, Jurgen Lemiere, Line Elmerdahl Frederiksen, Luzius Mader, Cecilia Follin, Sara Oberti, Jeanette Falck Winther, Selina R. van den Oever, Leontien C. M. Kremer, Helena J. H. van der Pal, Peter Spreeuwenberg, Eline Bouwman, Jeroen te Dorsthorst, Samira Essiaf, Elizabeth A. M. (Lieke) Feijen, Hannah Gsell, Riccardo Haupt, Maria van Helvoirt, Rosella P. M. G. Hermens, Lars Hjorth, Tomas Kepak, Katerina Kepakova, Anita Kienesberger, Monica Muraca, Marleen Renard, Carina Schneider, Roderick Skinner, Anne Uyttebroeck, Deveny Vanrusselt, Sabine Verschueren, Jacqueline Loonen, Saskia M. F. Pluijm, Katharina Roser, the PanCareFollowUp consortium   +36 more
wiley   +1 more source

Traumatic Brain Injuries during Development: Implications for Alcohol Abuse

Frontiers in Behavioral Neuroscience, 2017
Traumatic brain injuries are strongly related to alcohol intoxication as by some estimates half or more of all brain injuries involve at least one intoxicated individual.
Zachary M. Weil, Kate Karelina
doaj   +1 more source

The effects of marijuana use prior to traumatic brain injury on survival

Interdisciplinary Neurosurgery, 2021
Background: Legalization of recreational marijuana throughout the United States has been associated with increased emergency department visits involving marijuana and its metabolites, tetrahydrocannabinol (THC) and cannabinoids.
John J. Leskovan, Puja D. Patel, John Pederson, Aaron Moore, Amer Afaneh, Laura R. Brown   +5 more
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source