Traumatic brain injury and post-injury sleep fragmentation differentially alter the microglial transcriptome [PDF]
Frontiers in ImmunologyIntroductionTraumatic brain injury (TBI) is a global source of injury-related death and disability, and survivors often suffer functional and psychiatric consequences that persist for years.
Morgan A. Taylor +25 more
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Chronic Traumatic Encephalopathy (CTE) - An Update and Overview
Advances in Clinical Neuroscience & Rehabilitation, 2023 Chronic traumatic encephalopathy (CTE) is a neurodegenerative tauopathy associated with cumulative, prolonged exposure to symptomatic (concussive) or asymptomatic (subconcussive) repetitive head injuries (RHIs).
Rowena Mobbs
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Brain age in chronic traumatic brain injury
NeuroImage: Clinical, 2022 Traumatic brain injury (TBI) is associated with greater ‘brain age’ that may be caused by atrophy in grey and white matter. Here, we investigated ‘brain age’ in a chronic TBI (≥10 years) sample.
Gershon Spitz +4 more
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Neural Regeneration Research, 2022 A chronic phase following repetitive mild traumatic brain injury can present as chronic traumatic encephalopathy in some cases, which requires a neuropathological examination to make a definitive diagnosis.
Chu-Xin Huang +6 more
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Neural Regeneration Research, 2021 Traumatic brain injury is a sudden trauma or blow on the head, and severe traumatic brain injury is a major cause of death and disability worldwide. The acute and chronic consequences following traumatic brain injury can lead to progressive secondary ...
Asit Kumar, Santosh Kumar
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Persistent Infiltration and Impaired Response of Peripherally-Derived Monocytes after Traumatic Brain Injury in the Aged Brain. [PDF]
, 2018 Traumatic brain injury (TBI) is a leading cause for neurological disabilities world-wide. TBI occurs most frequently among the elderly population, and elderly TBI survivors suffer from reduced recovery and poorer quality of life. The effect of age on the
Chou, Austin +4 more
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Thalamic inflammation after brain trauma is associated with thalamo-cortical white matter damage [PDF]
, 2015 Background Traumatic brain injury can trigger chronic neuroinflammation, which may predispose to neurodegeneration. Animal models and human pathological studies demonstrate persistent inflammation in the thalamus associated with axonal injury, but this ...
Brooks, DJ +5 more
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Neurological consequences of traumatic brain injuries in sports. [PDF]
, 2015 Traumatic brain injury (TBI) is common in boxing and other contact sports. The long term irreversible and progressive aftermath of TBI in boxers depicted as punch drunk syndrome was described almost a century ago and is now widely referred as chronic ...
Hardy, J, Ling, H, Zetterberg, H
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Peripheral nerve injury is associated with chronic, reversible changes in global DNA methylation in the mouse prefrontal cortex. [PDF]
PLoS ONE, 2013 Changes in brain structure and cortical function are associated with many chronic pain conditions including low back pain and fibromyalgia. The magnitude of these changes correlates with the duration and/or the intensity of chronic pain.
Maral Tajerian +7 more
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Pharmacological Blockade of the Calcium Plateau Provides Neuroprotection Following Organophosphate Paraoxon Induced Status Epilepticus in Rats [PDF]
, 2016 Organophosphate (OP) compounds which include nerve agents and pesticides are considered chemical threat agents. Currently approved antidotes are crucial in limiting OP mediated acute mortality.
Ajdacic-Gross +43 more
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