Results 241 to 250 of about 670,754 (306)

From Cerebrovascular Injury to Vascular Cognitive Impairment and Dementia: Therapeutic Potential of Stem Cell-Derived Extracellular Vesicles. [PDF]

Biomedicines
Sigdel S, Sawant H, Yu BX, Chen A, Albalawy R, Wang J.   +5 more
europepmc   +1 more source

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

Advanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu, Jia‐Rui Bi, Zong‐Yan Yu, Meng Tian, Zhi‐Yue Chen, Ran Wei, Miao‐Miao Wang, Hai‐Wei Zha, Yu‐Qing Zhang, Hong‐Jing Wang, Bang‐You Qiang, Shuang‐Shuang Sun, Xiao‐Juan Zhu, Wen‐Bing Chen, Dong Sun   +14 more
wiley   +1 more source

High-Altitude Hypoxia Injury: Systemic Mechanisms and Intervention Strategies on Immune and Inflammatory Responses. [PDF]

Antioxidants (Basel)
Zhang J, Guo S, Dou B, Liu Y, Wang X, Jiao Y, Li Q, Li Y, Chen H.   +8 more
europepmc   +1 more source

Mesoscale Recovery of Microglial and Neuronal Dynamics After Craniotomy Across Wide Cortex in Transgenic Mice

Advanced Science, EarlyView.
This study employs longitudinal fluorescence imaging in transgenic mice to map post‐craniotomy cortical recovery. We identify distinct neuroimmune recovery phases: microglial structural inflammation peaks at ∼10 days, neuronal structural intensity peaks at ∼14 days and correlates with microglial activity, and functional network modularity is most ...
Guihua Xiao, Zhilei Wang, Pengchang Zheng, Jingyu Xie, Yangzhen Wang, Yun Chen, Zilin Wang, Ao Li, Minghuan Wang, Quanbo Ji, Can Gao, Di Yao, Lingbo Li, Jiangbei Cao   +13 more
wiley   +1 more source

Integrated Blood Biomarker and Neurobehavioural Signatures of Latent Neuroinjury in Experienced Military Breachers Exposed to Repetitive Low-Intensity Blast. [PDF]

Int J Mol Sci
Di Battista AP, Shiu MY, Vartanian O, Tenn C, Nakashima A, Vallikanthan J, Lam T, Rhind SG.   +7 more
europepmc   +1 more source

Repositioning of Alogliptin to Mitigate Secondary Injury Induced by Repetitive TBI: Potential Role of its Antioxidant and Anti- Inflammatory Effects. [PDF]

J Neuroimmune Pharmacol
Raslan HA, Michel HE, Menze ET, El-Gazar AA.   +3 more
europepmc   +1 more source

Brain networking pain and anxiety: From basic mechanism to future treatment. [PDF]

Mol Pain
Zhuo M.
europepmc   +1 more source

Emerging roles for interleukin-11 in the inflammatory response of intracerebral hemorrhage. [PDF]

Front Neurol
Xue L, Zhu J, Wang H, Wang Z, Yu W.
europepmc   +1 more source

Differential Cortico-Thalamic reorganization in Opioid-Induced hyperalgesia and neuropathic pain male rats. [PDF]

Neurobiol Pain
Cai A, Liu Q, Zhou W, Zheng D, Zhang W, Liu X, Nilufar M, Manyande A, Gao F, Wang J, Fang J, Tian X.   +11 more
europepmc   +1 more source