Results 71 to 80 of about 5,078,888 (363)
Neuroimmunology of Traumatic Brain Injury: Time for a Paradigm Shift
SUMMARY Traumatic brain injury (TBI) is a leading cause of morbidity and disability, with a considerable socioeconomic burden. Heterogeneity of pathoanatomical subtypes and diversity in the pathogenesis and extent of injury contribute to differences in ...
Yasir N. Jassam +4 more
semanticscholar +1 more source
This presentation will review empirically supported best practices for the screening and diagnosis of Attention Deficit Hyperactivity Disorder (ADHD) in adults. It will cover who to screen and how to screen, the diagnostic process, and specific tools and
L. Marriott +5 more
semanticscholar +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Capacity of astrocytes to promote axon growth in the injured mammalian central nervous system
Understanding the regulation of axon growth after injury to the adult central nervous system (CNS) is crucial to improve neural repair. Following acute focal CNS injury, astrocytes are one cellular component of the scar tissue at the primary lesion that ...
Matin Hemati-Gourabi +5 more
doaj +1 more source
Mild traumatic brain injury (mTBI), commonly known as concussion, is one of the most common neurologic disorders [1]. Based on emergency room visits, hospitalizations, and deaths, an estimated 1.7 million people sustain a traumatic brain injury (TBI) annually in the United States [2]. About 80% of TBIs that occur each year are mild TBI [3].
Greenwald, Brian D. +2 more
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Sex & gender considerations in concussion research
The study of concussion, a common form of mild traumatic brain injury, has received increased notice over the last decade. Recently, more researchers have been addressing the historic paucity of attention over sex and gender influences on recovery ...
Tatyana Mollayeva +2 more
doaj +1 more source
Ferroptosis contributes to neuronal death and functional outcome after traumatic brain injury.
Objectives: Traumatic brain injury triggers multiple cell death pathways, possibly including ferroptosis—a recently described cell death pathway that results from accumulation of 15-lipoxygenase–mediated lipid oxidation products, specifically oxidized ...
Elizabeth M. Kenny +10 more
semanticscholar +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Do sleep difficulties exacerbate deficits in sustained attention following traumatic brain injury? [PDF]
Sustained attention has been shown to be vulnerable following traumatic brain injury (TBI). Sleep restriction and disturbances have been shown to negatively affect sustained attention. Sleep disorders are common but under-diagnosed after TBI.
Espie, C.A. +5 more
core +1 more source

