Results 81 to 90 of about 690,249 (294)
Timing and Predictive Value of Clinical Conditions Preceding Multiple Sclerosis in the UK Biobank
ABSTRACT Objectives Multiple sclerosis (MS) patients often experience a higher incidence of clinical conditions before diagnosis, suggesting a prodromal phase. However, their predictive value and temporal trajectories remain underexplored. We investigated these aspects using the large UK Biobank's population‐based cohort, which provided clinical ...
Andrea Nova+5 more
wiley +1 more source
Association of the ICH Score With Withdrawal of Life‐Sustaining Treatment Over a 10‐Year Period
ABSTRACT Objective The intracerebral hemorrhage (ICH) score was developed to enhance provider communication and facilitate early severity assessment. We examined the association of the ICH score with mortality and withdrawal of life‐sustaining treatment (WLST) in a large, multicenter stroke registry, and evaluated temporal trends in these associations.
Nina Massad+15 more
wiley +1 more source
ABSTRACT Purpose This study aimed to explore the association between quantitative shape irregularity and density heterogeneity of hematomas and hematoma expansion (HE) for intracerebral hemorrhage (ICH) patients. Methods This cohort study included patients arriving within 24 h of symptom onset between August 2021 and July 2022 as the derivation cohort ...
Zeqiang Ji+11 more
wiley +1 more source
OBSERVATIONS IN THE DIAGNOSIS AND TREATMENT OF BRAIN INJURIES IN ADULTS [PDF]
William Sharpe
openalex +1 more source
ABSTRACT Objective To estimate the risk of epilepsy associated with stroke in a community‐based cohort, with consideration of stroke type, number, and severity. Methods Data from 15,100 Atherosclerosis Risk in Communities (ARIC) Study participants without stroke at baseline (1987–1989) were analyzed through 12/31/2022.
Jiping Zhou+11 more
wiley +1 more source
Neurotrophin-3 (NT-3) plays a key role in the growth, development, and function of the nervous system. Here the authors show that NT-3-induced propriospino-motoneuron circuit reorganization is critical for locomotor recovery in mice following spinal cord
Qi Han+12 more
doaj +1 more source
MANAGEMENT OF HEAD INJURIES WITH REAL OR POTENTIAL BRAIN DAMAGE [PDF]
Charles E. Dowman
openalex +1 more source
Objective This study aimed to identify themes contributing to resilience in childhood‐onset systemic lupus erythematosus (cSLE), distinguish between profiles of resilience, and examine how they relate to underlying themes and patient characteristics. Methods We conducted a mixed‐methods study of 21 patients with cSLE aged 11 to 19 years at a Canadian ...
Isabella Zaffino+12 more
wiley +1 more source
Delayed and progressive damages to juvenile mice after moderate traumatic brain injury
Symptoms are commonly more severe in pediatric traumatic brain injury (TBI) patients than in young adult TBI patients. To understand the mechanism, juvenile mice received a controlled cortical impact (CCI) injury at moderate level. Tissue lesion and cell
Shu Zhao+3 more
doaj +1 more source
Background In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of a scleroderma patient's ...
Ji Soo Kim+18 more
wiley +1 more source