Results 91 to 100 of about 2,710,974 (373)

Middle cerebral artery remodeling following transient brain ischemia is linked to early postischemic hyperemia: a target of uric acid treatment.

American Journal of Physiology. Heart and Circulatory Physiology, 2015
Ischemia impairs blood supply to the brain, and reperfusion is important to restore cerebral blood flow (CBF) and rescue neurons from cell death. However, reperfusion can induce CBF values exceeding the basal values before ischemia. This hyperemic effect
Y. Onetti, A. Dantas, B. Pérez, Roger Cugota, Á. Chamorro, A. Planas, E. Vila, F. Jiménez-Altayó   +7 more
semanticscholar   +1 more source

Associations of Stroke With Risk of Epilepsy: Results From the Atherosclerosis Risk in Communities (ARIC) Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To estimate the risk of epilepsy associated with stroke in a community‐based cohort, with consideration of stroke type, number, and severity. Methods Data from 15,100 Atherosclerosis Risk in Communities (ARIC) Study participants without stroke at baseline (1987–1989) were analyzed through 12/31/2022.
Jiping Zhou, Asma A. Ladak, Connor A. Law, Michelle C. Johansen, Anny Reyes, Silvia Koton, Sean Kelly, Jeubin Huang, Kamakshi Lakshminarayan, Rebecca F. Gottesman, Emily Johnson, Andrea L. C. Schneider   +11 more
wiley   +1 more source

Qingkailing injection ameliorates cerebral ischemia-reperfusion injury and modulates the AMPK/NLRP3 Inflammasome Signalling pathway

BMC Complementary and Alternative Medicine, 2019
Background Cerebral ischemia is the second-leading cause of death and the main cause of permanent adult disabilities worldwide. Qingkailing (QKL) injection, a patented Chinese medicine approved by the China Food and Drug Administration, has been widely ...
Chongyang Ma, Xueqian Wang, Tian Xu, Xue Yu, Shuang Zhang, Shuling Liu, Yushan Gao, Shuning Fan, Changxiang Li, Changming Zhai, Fafeng Cheng, Qingguo Wang   +11 more
doaj   +1 more source

Effects of pyruvate administration on infarct volume and neurological deficits following permanent focal cerebral ischemia in rats [PDF]

, 2003
Recent experimental evidences indicate that pyruvate, the final metabolite of glycolysis, has a remarkable protective effect against different types of brain injury.
Candelario-Jalil, Eduardo, Garcia-Cabrera, Michel, Gonzalez-Falcon, Armando, Leon, Olga S.   +3 more
core  

Isolation and Characterization of Ischemia-Derived Astrocytes (IDAs) with Ability to Transactivate Quiescent Astrocytes [PDF]

, 2016
Reactive gliosis involving activation and proliferation of astrocytes and microglia, is a widespread but largely complex and graded glial response to brain injury.
Barbeito, Osvaldo Luis, Cadena, María Vanesa, Dodes Traian, Martín Miguel, Murta, Verónica, Ramos, Alberto Javier, Rosciszewski, Gerardo Ariel, Setton, Clara Patricia, Usach, Vanina, Villarreal, Alejandro   +8 more
core   +1 more source

Central Dysmyelination in SSADH‐Deficient Humans and Mice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer, Henry H. C. Lee, Edward Yang, Cesar Alves, Mariarita Bertoldi, Caitlyn Fung, Spencer V. Steele, Eren Kule, Zijie Jin, Alexander Rotenberg, Jean‐Baptiste Roullet, Phillip L. Pearl   +11 more
wiley   +1 more source

The effect of beet leaf (Beta vulgaris) extract on learning and memory after cerebral ischemic reperfusion in rats

Future Natural Products
Background and aims: Cerebral ischemia causes tissue oxidative damage and leads to cell death. Antioxidants can reduce the adverse effects of ischemia in the brain.
Kobra Mirahmadi, Najmeh Asgharzadeh, Zahra Lorigooini, Marzieh Mardani, Zahra Rabiei, Diana Shahrani, Mohamad Shahrani, Mehrdad Shahrani Korrani   +7 more
doaj   +1 more source

Study of protein expresion [sic] in peri-infarct tissue after cerebral ischemia [PDF]

, 2015
In this work, we report our study of protein expression in rat peri-infarct tissue, 48 h after the induction of permanent focal cerebral ischemia. Two proteomic approaches, gel electrophoresis with mass spectrometry and combined fractional diagonal ...
Agulla, Jesús, Blanco, Miguel, Brea, David, Campos, Francisco, Castillo, José, Dávalos, Antoni, Gevaert, Kris, Ramos-Cabrer, Pedro, Sobrino, Tomás, Staes, An   +9 more
core   +5 more sources

Effects of irisin on the dysfunction of blood–brain barrier in rats after focal cerebral ischemia/reperfusion

Brain and Behavior, 2019
To investigate whether irisin could protect against blood–brain barrier (BBB) dysfunction following focal cerebral ischemia/reperfusion in rats.
Peipei Guo, Zhao Jin, Huisheng Wu, Xinyi Li, J. Ke, Zongze Zhang, Qiu Zhao   +6 more
semanticscholar   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source