Results 111 to 120 of about 237,616 (316)
, 2000 Recent studies of transient focal ischemia have focused interest on apoptotic mechanisms of neuronal cell death involving constitutive pro-apoptotic proteins.
Jessie Truettner +13 more
core +1 more source
Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon +5 more
wiley +1 more source
CD147 as a key mediator of the spleen inflammatory response in mice after focal cerebral ischemia
Journal of Neuroinflammation, 2019 Background The splenic inflammatory response after cerebral ischemia has been implicated in secondary brain injury. We have recently reported that CD147 plays an important role in driving brain inflammation after ischemic stroke.
Rong Jin +3 more
doaj +1 more source
Reperfusion of ischemia in the heart or brain
The Journal of Pharmacology and Experimental TherapeuticsThe current treatment of choice for an acute myocardial infarction (AMI) is an interventional procedure like percutaneous coronary intervention (PCI), which takes 2 to 3 hours and is not appropriate for clots in arteries smaller than the catheter.
Victor Gurewich, David Segarnick
openaire +2 more sources
, 1998 Background and Purpose-Cerebral arteriolar dilation to N-methyl-D-aspartate (NMDA) is a neuronally mediated multistep process that is sensitive to cerebral hypoxia and ischemia (H/I).
Domoki, Ferenc +2 more
core
Glucose availability and sensitivity to anoxia of isolated rat peripheral nerve [PDF]
, 1991 The contrast between resistance to ischemia and ischemic lesions in peripheral nerves of diabetic patients was explored by in vitro experiments. Isolated and desheathed rat peroneal nerves were incubated in the following solutions with different glucose ...
R. Jund +7 more
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White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian +8 more
wiley +1 more source
Медицинский вестник Юга России, 2013 The methodology of brain protection from acute ischemic damage is a primary aim of modern pharmacology. The paper represents a review of modern drugs diminishing brain ischemia subsequences. The most important directions of neuroprotection are determined
E. V. Gantsgorn +2 more
doaj +1 more source
, 2001 The time course of oxidative damage in different brain regions was investigated in the gerbil model of transient cerebral ischemia. Animals were subjected to both common carotid arteries occlusion for 5 min.
Candelario-Jalil, Eduardo +4 more
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Olanzapine attenuates brain damage after focal cerebral ischemia in vivo
, 2006 Atypical antipsychotic drugs are widely used in the treatment of schizophrenia. These agents are discovered to have some additional beneficial effects beyond their effectiveness as antipsychotic drugs.
Schaebitz, Wolf Ruediger +3 more
core +1 more source