Results 91 to 100 of about 1,985,012 (310)

Natriuretic peptide receptor-C regulates coronary blood flow and prevents myocardial ischemia/reperfusion injury: novel cardioprotective role for endothelium-derived C-type natriuretic peptide [PDF]

, 2004
Background: Ischemia/reperfusion (I/R) injury complicates myocardial infarction and stroke by exacerbating tissue damage and increasing risk of mortality.
Ramona Scotl, Hobbs, Adrian, Ahluwalia, Amrita, Foster, Paul, Hobbs, A., Phd Amrita Ahluwalia, Foster, P., Adrian Hobbs, Phd Paul Foster, Scotland, R., Prescott, Craig, Scotland, Ramona, Ahluwalia, A., Phd Craig Prescott, Natriuretic Peptide, Prescott, C.   +15 more
core   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source

METABOLIC AND BEHAVIORAL EFFECTS OF KETOGENIC AND NON-KETOGENIC LOW-CARBOHYDRATE DIETS

IBRO Neuroscience Reports, 2023
Ilya Smolensky, Kilian Zajac-Bakri, Catherine Brégère, Raphael Guzman, Dragos Inta   +4 more
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Neuroprotective Effects of Exercise on Brain Edema and Neurological Movement Disorders Following the Cerebral Ischemia and Reperfusion in Rats

Basic and Clinical Neuroscience, 2017
Introduction: Cerebral ischemia and reperfusion causes physiological and biochemical changes in the neuronal cells that will eventually lead to cell damage.
Nabi Shamsaei, Soheila Erfani, Masoud Fereidoni, Ali Shahbazi   +3 more
doaj  

Qingkailing injection ameliorates cerebral ischemia-reperfusion injury and modulates the AMPK/NLRP3 Inflammasome Signalling pathway

BMC Complementary and Alternative Medicine, 2019
Background Cerebral ischemia is the second-leading cause of death and the main cause of permanent adult disabilities worldwide. Qingkailing (QKL) injection, a patented Chinese medicine approved by the China Food and Drug Administration, has been widely ...
Chongyang Ma, Xueqian Wang, Tian Xu, Xue Yu, Shuang Zhang, Shuling Liu, Yushan Gao, Shuning Fan, Changxiang Li, Changming Zhai, Fafeng Cheng, Qingguo Wang   +11 more
doaj   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Set up of an in vitro ischemia model using immortalized-human brain microvascular endothelial cells (i-hBMECs) to study the activation of complement lectin pathway in stroke

, 2016
Introduction Mannose-binding lectin (MBL) is a protein of the lectin pathway (LP) complement cascade that plays a key role in ischemic stroke pathophysiology.
A. Bernardi, S. Fumagalli, M. Gobbi, M. G. De Simoni, G. Goti, S. Sormani, L. Neglia, C. Perego, V. Hubert, M. Wiart   +9 more
core   +2 more sources

Oxidative Stress in Brain Ischemia

Brain Pathology, 1999
Brain ischemia initiates a complex cascade of metabolic events, several of which involve the generation of nitrogen and oxygen free radicals. These free radicals and related reactive chemical species mediate much of damage that occurs after transient brain ischemia, and in the penumbral region of infarcts caused by permanent ischemia.
openaire   +3 more sources

‘Functional histology’ in brain ischemia studies [PDF]

Journal of Cerebral Blood Flow & Metabolism, 2011
Classical histology and biochemistry constitute two very different ways to study biology. Classical histology allows direct visualization of tissue, but is limited by the non-specificity of organic dyes and the need to stain fixed tissue in postmortem samples.
openaire   +3 more sources