Results 131 to 140 of about 2,710,974 (373)
CD147 as a key mediator of the spleen inflammatory response in mice after focal cerebral ischemia
Journal of Neuroinflammation, 2019 Background The splenic inflammatory response after cerebral ischemia has been implicated in secondary brain injury. We have recently reported that CD147 plays an important role in driving brain inflammation after ischemic stroke.
Rong Jin +3 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.The tissue and functional benefits are demonstrated with local, sustained delivery of an anti‐inflammatory peptide, pituitary adenylate cyclase‐activating polypeptide (PACAP), for stroke treatment in a mouse model. Prolonged PACAP treatment modulated astrocyte and microglia toward pro‐reparative phenotypes, enhanced neuroprotection and preservation of ...
Eric Ho +7 more
wiley +1 more source
Stem Cell Research & Therapy, 2017 Background Blood-brain barrier impairment is a major indicator of endothelial dysfunction in diabetes. Studies showed that endothelial progenitor cell (EPC) transplantation promoted angiogenesis and improved function recovery after hind limb ischemia in ...
Jieli Geng +10 more
doaj +1 more source
Vulnerability of white matter to ischemia varies during development [PDF]
, 2011 Stroke is the one of the leading causes of mortality and morbidity in developed countries. The central role of injury to white matter in the pathophysiology of stroke has been recognised over the recent years.
Di Giovanni, Giuseppe +4 more
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Advanced Healthcare Materials, EarlyView.This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail +3 more
wiley +1 more source
Neurobiology of Disease, 2013 Application of isoflurane, a volatile anesthetic, after brain ischemia can reduce ischemic brain injury in rodents (isoflurane postconditioning). This study is designed to determine whether isoflurane postconditioning improves long-term neurological ...
Hong Li +5 more
doaj
Бюллетень сибирской медицины, 2008 The purpose of present research is to estimate the correlation between vegetative dysfunction and cognitive impairment in patients with chronic ischemia of the brain. We supervised 112 patients with chronic ischemia of the brain.
T. V. Mokina +3 more
doaj +1 more source
NOX Inhibitors - A Promising Avenue for Ischemic Stroke. [PDF]
, 2017 NADPH-oxidase (NOX) mediated superoxide originally found on leukocytes, but now recognized in several types of cells in the brain. It has been shown to play an important role in the progression of stroke and related cerebrovascular disease.
Kim, Jong Youl +3 more
core +1 more source
Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases
Advanced Healthcare Materials, EarlyView.This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun +9 more
wiley +1 more source
Inflammation Combined with Ischemia Produces Myelin Injury and Plaque-Like Aggregates of Myelin, Amyloid-β and AβPP in Adult Rat Brain. [PDF]
, 2015 BackgroundIschemia, white matter injury, and Alzheimer's disease (AD) pathologies often co-exist in aging brain. How one condition predisposes to, interacts with, or perhaps causes the others remains unclear.ObjectivesTo better understand the link ...
Ander, Bradley P +7 more
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