CD8<sup>+</sup>GZMK<sup>+</sup>CD27<sup>+</sup>CCR7<sup>+</sup> T cells mobilized by splenic sympathetic nerves aggravate brain ischemia‒reperfusion injury via CCL19-positive endothelial cells. [PDF]
Bai Y +21 more
europepmc +1 more source
Phagocytosis executes delayed neuronal death after focal brain ischemia
J. Neher +5 more
semanticscholar +1 more source
Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes
Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako +16 more
wiley +1 more source
Modulating the RPS27A/PSMD12/NF-κB pathway to control immune response in mouse brain ischemia-reperfusion injury. [PDF]
Li X +6 more
europepmc +1 more source
Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia.
J. Yrjänheikki +4 more
semanticscholar +1 more source
P-glycoprotein expression in brain during ischemia-reperfusion
E. N. Yakusheva +3 more
openalex +2 more sources
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin +18 more
wiley +1 more source
A mechanistic systems biology model of brain microvascular endothelial cell signaling reveals dynamic pathway-based therapeutic targets for brain ischemia. [PDF]
Li G +14 more
europepmc +1 more source
Ionic Transporter Activity in Astrocytes, Microglia, and Oligodendrocytes During Brain Ischemia
L. Annunziato, F. Boscia, G. Pignataro
semanticscholar +1 more source
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang +5 more
wiley +1 more source

