Results 141 to 150 of about 1,655,573 (298)
Med Research, EarlyView.This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng +14 more
wiley +1 more source
Frontiers in ImmunologyThe central nervous system has long been considered an immune-privileged organ, but discoveries about meningeal lymphatics, meningeal immune cells, cerebrospinal fluid (CSF)-interstitial fluid (ISF) exchange, and aquaporin-4 (AQP4)-associated glymphatic ...
Xiaolei Wu +5 more
doaj +1 more source
Forgotten findings of brain lymphatics [PDF]
Nature, 2015 Éva Mezey, Miklós Palkovits
openaire +1 more source
Organoid Coculture Models for Cancer Research and Immunotherapy
Med Research, EarlyView.This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang +9 more
wiley +1 more source
ABC of Brain Stem Death: From Brain Death to Brain Stem Death
, 1982 In the second in a series of nine articles on brain death, a British neurologist traces the evolution of British and American criteria for establishing brain death, distinguishes between whole brain death and death of the brain stem, and describes the ...
Pallis, Christopher
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Cellular Contributions to Glymphatic and Lymphatic Waste Clearance in the Brain
Cold Spring Harbor Perspectives in BiologyCerebrospinal fluid (CSF) bathes and cushions the brain; however, it also serves a major role in the clearance of metabolic wastes and in the distribution of glucose, lipids, and amino acids. Unlike every other organ in the body, the brain parenchyma lacks a traditional lymphatic system to drain fluids and central nervous system (CNS) antigens.
Smyth, Leon C.D. +3 more
openaire +2 more sources
PM&R, EarlyView.Abstract Background Hypovitaminosis D is associated with adverse health outcomes, including increased mortality in patients with cancer. Although vitamin D insufficiency (23%–72%) and deficiency (20%–71%) are common among patients admitted to inpatient rehabilitation, their prevalence and predictors in cancer‐specific inpatient rehabilitation ...
Jegy M. Tennison +7 more
wiley +1 more source
Human Prostate Cell Lines: Derivation, Molecular Characteristics and Appropriate Use
The Prostate, EarlyView.ABSTRACT Background Research on prostate cancer and benign prostatic hyperplasia depends on a small number of immortalized human cell lines established between 1977 and 2001, most of them from advanced metastatic disease. The cell lines differ from one another in androgen receptor status, prostate‐specific antigen secretion, p53 status, karyotype and ...
Hamza Abohamra, Keenau Mark Pearce
wiley +1 more source
Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy
Phytotherapy Research, EarlyView.This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi +9 more
wiley +1 more source
Orbital lymphatics: do they exist?
Introduction Although the lymphatic system was first described almost 400 years ago, it is only in very recent years that researchers have been able to identify lymphatic channels with reasonable accuracy.
Gausas RE, Dickinson AJ
core +4 more sources