Results 91 to 100 of about 3,008,515 (314)

Self-related thought alterations associated with intrinsic brain dysfunction in mild cognitive impairment

Scientific Reports
The subjective experience of self-awareness is attributed to the human capacity for introspective thought during periods of mind-wandering. However, how this cognitive function is impacted in individuals with mild cognitive impairment (MCI) still needs ...
Povilas Tarailis, Kim Lory, Paul G. Unschuld, Christoph M. Michel, Lucie Bréchet   +4 more
doaj   +1 more source

CamBAfx: workflow design, implementation and application for neuroimaging

Frontiers in Neuroinformatics, 2009
CamBAfx is a workflow application designed for both researchers who use workflows to process data (consumers) and those who design them (designers). It provides a front-end (user interface) optimized for data processing designed in a way familiar to ...
Cinly Ooi, Cinly Ooi, Edward T Bullmore, Edward T Bullmore, Alle-Meije Wink, Levent Sendur, Levent Sendur, Anna Barnes, Anna Barnes, Sophie Achard, Sophie Achard, John Aspden, Sanja Abbott, Shigang Yue, Manfred Kitzbichler, David Meunier, David Meunier, Voichita Maxim, Voichita Maxim, Raymond Salvador, Julian Henty, Julian Henty, Roger Tait, Roger Tait, Naresh Subramaniam, John Suckling, John Suckling   +26 more
doaj   +1 more source

Singapore 1:25,000 road map [cartographic material] /

, 2010
Planimetric map of Singapore showing selected buildings, points of interest, and schools.; Some sheets include insets.; Includes list of schools.
Singapore. Ministry of Defence. Mapping Unit.
core  

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Map of Norfolk Island [cartographic material] : Drawn and reproduced by the National Mapping Office, Dept. of the Interior.

, 1956
Relief shown by spot heights and contours. Contour at 100 ft.; "NMO/56/50"; Also available online http://nla.gov.au/nla.map-vn1758341.
Australia. National Mapping Office.
core  

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Modulation of habenular and nucleus accumbens functional connectivity by ketamine in major depression

Brain and Behavior
Introduction Major depressive disorder (MDD) is associated with dysfunctional reward processing, which involves functional circuitry of the habenula (Hb) and nucleus accumbens (NAc).
Brandon Taraku, Joana R. Loureiro, Ashish K. Sahib, Artemis Zavaliangos‐Petropulu, Noor Al‐Sharif, Amber M. Leaver, Benjamin Wade, Shantanu Joshi, Roger P. Woods, Randall Espinoza, Katherine L. Narr   +10 more
doaj   +1 more source

Subcortical electrophysiological activity is detectable with high-density EEG source imaging

Nature Communications, 2019
Electroencephalography (EEG) allows the measurement of electrical signals associated with brain activity, but it is unclear if EEG can accurately measure subcortical activity.
Martin Seeber, Lucia-Manuela Cantonas, Mauritius Hoevels, Thibaut Sesia, Veerle Visser-Vandewalle, Christoph M. Michel   +5 more
doaj   +1 more source