Results 111 to 120 of about 2,048,757 (259)

Breast Cancer Associated Metastasis is Significantly Increased in a Model of Autoimmune Arthritis [PDF]

, 2008
Chronic inflammation is known to play a role in cancer initiation, promotion,and metastasis. However, the mechanism by which inflammation promotes metastasis is still unclear.
Latha Pathangey, Pinku Mukherjee, Teresa Tinder, Lopamudra Das Roy   +3 more
core  

Multiscale Spatial Fusion Feature‐Driven Characterization of Gastric Cancer Invasive Margins: A Multicenter Cohort Study for Preoperative Accurate Differentiation Between T4a and T4b Subtypes

Advanced Science, EarlyView.
This study develops a multi‐dimensional vision Transformer‐based model, GAVR, to accurately distinguish gastric cancer T4a/b stages preoperatively. Validated across multi‐center cohorts, it achieves excellent performance and significantly improves radiologists’ diagnostic accuracy, offering a promising tool for clinical decision‐making.
Guoliang Zheng, Xiaomiao Chai, Peng Jin, Xin Xin, Yingjie Li, Chun Yang, Jia Wei, Zishuo Yan, Jingyu Zhang, Qianning Zhao, Yingchen Han, Ning Zhang, Fuze Li, Bo Qiao, Huan Wang, Huachuan Zheng, Yan Li, Xin Zhang, Yan Zhao, Wenjun Mao, Jing Zhang   +20 more
wiley   +1 more source

Management of patients with metastasis to the vertebrae: recommendations from the Italian Orthopaedic Society (SIOT) Bone Metastasis Study Group

, 2014
The purpose of this article is to outline the current approach to patients affected by metastasis to the spine and to present a clinical and surgical algorithm available for clinicians and for future research.
Casadei, Roberto, Spinelli, Maria Silvia, Capanna, Rodolfo, Boriani, Stefano, Papapietro, Nicola, The Italian Orthopaedic Society Bone Metastasis Study Group, Gasbarrini, Alessandro, Piccioli, Andrea, Di martino, Alberto   +8 more
core   +1 more source

Label‐Free Myelin Fingerprinting: An Adult Human Post‐Mortem Brain Slice Platform via Coherent Anti‐Stokes Raman Spectroscopy

Advanced Science, EarlyView.
A serum‐free, air–liquid interface organotypic slice culture model preserves human post‐mortem corpus callosum tissue, successfully recovering from slicing trauma to reflect the donor's underlying disease state. Pairing label‐free Coherent anti‐Stokes Raman scattering (CARS) microscopy with k‐means clustering enables objective, high‐resolution ...
Kasra Roya‐Kouchaki, Jeroen P. Korterik, Femke Tjebbes, Geert J. Schenk, Herman L. Offerhaus, Antonio Luchicchi   +5 more
wiley   +1 more source

An immune-competent model of spontaneous breast cancer metastasis to the brain

, 2011
In breast cancer, brain metastases are often seen as late complications of recurrent disease and represent a particularly serious condition, since there are limited therapeutic options and patients have an unfavorable prognosis.
Kuonen, F., Lan, Q., Ruegg, C., Lorusso, G.   +3 more
core  

Diagnostics and Screening in Breast Cancer with Brain and Leptomeningeal Metastasis: A Review of the Literature

Brain and leptomeningeal metastases are complications of breast cancer with high rates of morbidity and mortality and have an estimated incidence of up to 30%.
Adam J. Cohen-Nowak, Virginia B. Hill, Priya Kumthekar   +2 more
core   +1 more source

Characteristics and Treatments of Large Cystic Brain Metastasis: Radiosurgery and Stereotactic Aspiration [PDF]

, 2015
Brain metastasis represents one of the most common causes of intracranial tumors in adults, and the incidence of brain metastasis continues to rise due to the increasing survival of cancer patients. Yet, the development of cystic brain metastasis remains
Kim, Moinay, Kwon, Do Hoon, Cheok, Stephanie, Voth, Brittany, Chung, Lawrance K, Kim, Chang Jin, Kim, Jeong Hoon, Ung, Nolan, Thill, Kimberly, Yang, Isaac, Tenn, Stephen, Lee, Percy   +11 more
core   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

Antiplatelet Therapy Mitigates Brain Metastasis Risk in Non-Small Cell Lung Cancer: Insights from a Comprehensive Retrospective Study

Background: Brain metastases are a common and devastating complication of non-small cell lung cancer (NSCLC), severely affecting prognosis and quality of life.
María García-Gil, Margarita Méndez-Monge, Helga Fariña-Jerónimo, Carla Martín-Abreu, Julio Plata-Bello   +4 more
core   +1 more source

Brain Metastasis in Endometrial Cancer: A Systematic Review [PDF]

Background: Brain metastases (BMs) from endometrial cancer (EC) are rare and challenging to treat, with limited standardized guidelines. This systematic review aims to evaluate the incidence, therapeutic strategies, and outcomes associated with brain ...
Andrea Maria Onofrio Quattrocchi, Giuseppe Scibilia, Gebbia, Vittorio, Salvatore Lavalle, Basilio Pecorino, Valerio, Maria Rosaria, Bonasera, Annalisa, Annalisa Bonasera, Giuseppe Caputo, Vittorio Gebbia, Vinci, Ernesto, Quattrocchi, Andrea Maria Onofrio, Danilo Centonze, Lavalle, Salvatore, Centonze, Danilo, Giuseppa Scandurra, Maria Rosaria Valerio, Ernesto Vinci, Sambataro, Daniela, Daniela Sambataro, Caputo, Giuseppe, Scibilia, Giuseppe, Pecorino, Basilio, Scandurra, Giuseppa, Di Mattia, Paolo, Paolo Di Mattia   +25 more
core   +1 more source