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Natriuretic peptides (NPs) are a family of prognostic biomarkers in patients with heart failure (HF). HF is one of the most frequent comorbidities in patients with chronic obstructive pulmonary disease (COPD).
R. Pavasini+10 more
semanticscholar +1 more source
Brain Natriuretic Peptides as Biomarkers for Atherosclerosis [PDF]
Identification of atherosclerotic risk factors provides targets for development of preventive therapies. Risk factor assessment permits evaluation of an individual's prospective risk of coronary heart disease (CHD). However, it has become apparent that traditional risk factors may not predict CHD in some patients.
Kellan E. Ashley+2 more
openaire +3 more sources
Detection of C-type natriuretic peptide (CNP) transcript in the rat heart and immune organs [PDF]
Previous studies suggested the expression of mRNA, coding for CNP, exclusively in the central nervous system. In the present study, using the polymerase chain reaction (PCR) technique instead of the less sensitive Northern blot hybridization, CNP ...
Gerbes, Alexander L.+3 more
core +1 more source
Background. B-type natriuretic peptide has been shown to be a very sensitive and specific marker of heart failure. In this study, we aimed to investigate the effect of percutaneous closure of ventricular septal defects with Amplatzer septal occluders on ...
Yuksel Kaya+11 more
doaj +1 more source
Physiology and clinical significance of natriuretic hormones
The natriuretic system consists of the atrial natriuretic peptide (ANP) and four other similar peptides including the wrongly named brain natriuretic peptide (BNP). Chemically they are small peptide hormones predominantly secreted by the cardiac myocytes
Sandeep Chopra+3 more
doaj +1 more source
Brain Natriuretic Peptide in Hypertension.
Brain natriuretic peptide (BNP) was first identified in the porcine brain and later isolated from porcine, rat, and human hearts. In humans, plasma BNP concentrations are progressively elevated with increasing severity of hypertension, particularly when left ventricular hypertrophy (LVH) is present.
Tadanao Takeda, Masakazu Kohno
openaire +4 more sources
Molecular Implications of natriuretic peptides in the protection from hypertension and target organ damage development [PDF]
The pathogenesis of hypertension, as a multifactorial trait, is complex. High blood pressure levels, in turn, concur with the development of cardiovascular damage.
Forte, Maurizio+3 more
core +1 more source
Natriuretic peptides and their usefulness in clinical practise
Natriuretic peptides are peptic hormones produced by atrial and ventricular myocytes, and by endothelium of blood vessels, that take part in homeostatic control of water and sodium levels, but also potassium transport, lipolysis in adipocytes and blood ...
Aleksandra Skałecka+5 more
doaj +1 more source
Molecular Mechanism of Blood Pressure Regulation through the Atrial Natriuretic Peptide
Natriuretic peptides, including atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP), have cardioprotective effects and regulate blood pressure in mammals.
Takeshi Tokudome, Kentaro Otani
doaj +1 more source
Background On trigeminal ganglion neurons, pain-sensing P2X3 receptors are constitutively inhibited by brain natriuretic peptide via its natriuretic peptide receptor-A. This inhibition is associated with increased P2X3 serine phosphorylation and receptor
A. Marchenkova+4 more
semanticscholar +1 more source