Results 31 to 40 of about 96,104 (260)

Natriuretic peptides are neuroprotective on in vitro models of PD and promote dopaminergic differentiation of hiPSCs-derived neurons via the Wnt/β-catenin signaling

Cell Death Discovery, 2021
Over the last 20 years, the efforts to develop new therapies for Parkinson’s disease (PD) have focused not only on the improvement of symptomatic therapy for motor and non-motor symptoms but also on the discovering of the potential causes of PD, in order
Daniela Giovannini, Federica Andreola, Paola Spitalieri, Ewa Krystyna Krasnowska, Arianna Colini Baldeschi, Simona Rossi, Federica Sangiuolo, Mauro Cozzolino, Annalucia Serafino   +8 more
doaj   +1 more source

Natriuretic peptides and integrated risk assessment for cardiovascular disease. an individual-participant-data meta-analysis [PDF]

, 2016
BACKGROUND: Guidelines for primary prevention of cardiovascular diseases focus on prediction of coronary heart disease and stroke. We assessed whether or not measurement of N-terminal-pro-B-type natriuretic peptide (NT-proBNP) concentration could enable ...
Adam S, Butterworth, Andreas, Luchner, Angela M, Wood, Brendan, M. Everett, Børge G, Nordestgaard, Caroline, N. Kistorp, Christie M, Ballantyne, Christopher, Defilippi, Daniel F, Freitag, Daniel, Levy, Demosthenes, B. Panagiotakos, DI ANGELANTONIO, EMANUELE, Frank, Kee, Goya Wannamethee, S, James A, de Lemos, Jari A. Laukkanen, Maryam Kavousi, Jens, Rosenberg, Johan, Ärnlöv, John, Danesh, Jonas, Andersson, Jorge R, Kizer, Juan Pablo, Casas, Jukka, T. Salonen, Jussi, Kauhanen, Lars, Lind, Lisa, Pennells, Lori B, Daniels, Mary, Cushman, Michael, Hecht Olsen, Michael, Sweeting, Nancy, R. Cook, Naveed, Sattar, Olle, Melander, Oscar, H. Franco, Paul M, Ridker, Pei, Gao, Peter, Willeit, Rajiv, Chowdhury, RUBATTU, Speranza Donatella, Rudolf, A. de Boer, Sarah, A. Spackman, Simon G, Thompson, Stefan, Kiechl, Stella, Trompet, Stephen Kaptoge, Paul Welsh, Stephen, Burgess, Suzanne, Judd, Thomas, Mueller, Torben, Jørgensen, Toshiharu, Ninomiya, Veikko, Salomaa, Vijay, Nambi, Vilmundur, Gudnason, Wayne, D. Rosamond   +53 more
core   +1 more source

A Multi-marker Model for Predicting Decompensated Heart Failure in Patients with Prior Acute Myocardial Infarction [PDF]

, 2020
The aim of the study was to assess the prognostic value of determining the plasma concentration of NT-proBNP and ST2 in the patients with decompensated HF and prior acute myocardial infarction and their combination in this category of patients.Materials ...
Levandovska, K. (Khrystyna)
core   +3 more sources

Natriuretic peptide receptor-C is up-regulated in the intima of advanced carotid artery atherosclerosis [PDF]

, 2016
OBJECTIVE: Natriuretic peptide receptor-C (NPR-C/NPR-3) is a cell surface protein involved in vascular remodelling that is up-regulated in atherosclerosis. NPR-C expression has not been well characterized in human carotid artery occlusive lesions.
Abendschein, Dana R, Detering, Lisa, Harring, Scott D, Liu, Yongjian, Lu, Dongsi, Vemuri, Chandu, Woodard, Pamela K, Zayed, Mohamed A   +7 more
core   +3 more sources

Combination of Amino‐Terminal Pro‐BNP, Estimated GFR, and High‐Sensitivity CRP for Predicting Cardiorenal Syndrome Type 1 in Acute Myocardial Infarction Patients

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Cardiorenal syndrome type 1 (CRS1) as a complication of acute myocardial infarction can lead to adverse outcomes, and a method for early detection is needed. This study investigated the individual and integrated effectiveness of amino‐terminal
De‐Qiang Zhang, Hong‐Wei Li, Hai‐Ping Chen, Qing Ma, Hui Chen, Yun‐Li Xing, Xue‐Qiao Zhao   +6 more
doaj   +1 more source

Resetting the neurohormonal balance in heart failure (HF). the relevance of the natriuretic peptide (NP) system to the clinical management of patients with HF [PDF]

, 2017
The natriuretic peptide (NP) system, which includes atrial natriuretic peptide, B-type natriuretic peptide, and C-type natriuretic peptide, has an important role in cardiovascular homeostasis, promoting a number of physiological effects including ...
Rubattu, Speranza Donatella, Triposkiadis, Filippos   +1 more
core   +2 more sources

N-Terminal Pro–B-Type Natriuretic Peptide in the Emergency Department: The ICON-RELOADED Study [PDF]

, 2018
Background Contemporary reconsideration of diagnostic N-terminal pro–B-type natriuretic peptide (NT-proBNP) cutoffs for diagnosis of heart failure (HF) is needed.
Chen-Tournoux, Annabel A., Christenson, Robert H., Doros, Gheorghe, Gaggin, Hanna K., Hollander, Judd E., Januzzi, James L., Levy, Phillip D., Nagurney, John T., Nowak, Richard M., Pang, Peter S., Patel, Darshita, Peacock, W. Franklin, Rivers, E. Joy, Walters, Elizabeth L.   +13 more
core   +1 more source

Natriuretic Peptides, Diagnostic and Prognostic Biomarkers [PDF]

, 2010
In humans, the natriuretic peptide family consists of three different types of peptides: atrial natriuretic peptide (synonym: atrial natriuretic factor), B-type natriuretic peptide (synonym: brain natriuretic peptide) and C-natriuretic peptide.1 ...
Rutten, J.H.W. (Joost)
core  

Discrimination and Quantification of Glomerular Receptor Subtypes for Atrial Natriuretic Factor (Anf) [PDF]

, 1991
Binding sites for atrial natriuretic factor (ANF) were determined on isolated rat glomeruli as well as on glomerular membranes. To define optimal conditions, binding of ANF was investigated varying incubation time, temperature and protein concentration ...
Gerbes, Alexander L., Kollenda, Margit C., Scarborough, Robert M.   +2 more
core   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source