Results 101 to 110 of about 227,738 (352)

Comparative Efficacy and Safety of Immunotherapy on Non–Small Cell Lung Cancer Patients With Brain Metastases: A Systematic Review and Network Meta‐Analysis

The Clinical Respiratory Journal
Background Growing evidence suggests that immunotherapy has a positive effect on non–small cell lung cancer (NSCLC) patients with brain metastases (BMs). However, it remains unclear which type of immunotherapy is more efficient.
Tianyi Lyu, Bo Sun, Daowen Yang, Xirui Zhao, Ruoshui Wang, Xinyang Shu, Demin Li, Hong Chen   +7 more
doaj   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

Efficacy of pembrolizumab plus lenvatinib as first‐line treatment for metastatic renal cell carcinoma with multiple brain metastases

IJU Case Reports
Introduction Patients with metastatic renal cell carcinoma have a poor prognosis and its specific pathogenesis remains unelucidated. Case presentation At 78 years of age, a Japanese male patient was diagnosed with metastatic renal cell carcinoma (cT3N2M1
Daisuke Matsumoto, Taku Naiki, Aya Naiki‐Ito, Maria Aoki, Shinji Kato, Toshiharu Morikawa, Nobuhiko Shimizu, Masakazu Gonda, Yukihiro Umemoto, Takahiro Yasui   +9 more
doaj   +1 more source

Erratum to: Stereotactic targeted radiation therapy (STaRT) trials for brain neoplasms: A comprehensive review. [PDF]

Neuro Oncol, 2023
Odia Y, Gutierrez AN, Kotecha R.
europepmc   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Consensus guidelines for the management of primary supra-tentorial intraventricular tumour for low- and middle-income countries

Journal of the Pakistan Medical Association
Almost any primary or metastatic brain tumour can manifest in intraventricular (IV) locations. These tumours may either originate within the ventricular system or extend into the IV space through growth.
Hafiza Fatima Aziz, Saqib Kamran Bakhshi, Rabeet Tariq, Muhammad Waqas Saeed Baqai, Mohammad Hamza Bajwa, Kaynat Siddiqui, Zanib Javed, Ahsan Ali Khan, Muhammad Shakir, Pakistan Brain Tumour Consortium: (Authors list at the end of the supplement), Syed Ather Enam   +10 more
doaj   +1 more source

Matrix: a complex amalgam of structures and functions in tumor microenvironment

FEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis, Evgenia Tsoukala, Theodora D. Sarantopoulou, Maria‐Elpida Christopoulou   +3 more
wiley   +1 more source

Associação entre fatores da dieta e tumores de cérebro em adultos: uma revisão da literatura

Cadernos de Saúde Pública
Desenvolveu-se uma revisão da literatura científica publicada entre 1986 e 1999, sobre a associação entre fatores da dieta e os tumores de cérebro em adultos, com o objetivo de descrever as associações observadas e discutir os aspectos metodológicos que ...
Rosângela Alves Pereira, Sérgio Koifman   +1 more
doaj