Proton therapy in the treatment of diffuse astrocytoma of the brain stem. Case report
Сибирский онкологический журнал, 2022 Background. Despite the fact that cerebral astrocytoma belongs to low-grade tumors (grade II gliomas), it often leads to disability and death of patients.
T. A. Kireeva +5 more
doaj +1 more source
Pontine Primitive Neuroectodermal Tumor With Spinal Metastasis in a 10-year-old Girl [PDF]
, 2010 Brain tumors are the most common type of solid cancer in children. Approximately 20% of pediatric brain tumors originate from the brain stem, and most are comprised of gliomas. However, metastasis of brain stem gliomas along the neuraxis is rare.
Chang, Yu-Ching +4 more
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Efficient generation of neural stem cell-like cells from adult human bone marrow stromal cells [PDF]
, 2004 Clonogenic neural stem cells (NSCs) are self-renewing cells that maintain the capacity to differentiate into brain-specific cell types, and may also replace or repair diseased brain tissue. NSCs can be directly isolated from fetal or adult nervous tissue,
Boehm, Bernhard O. +10 more
core
Human in vitro models for understanding mechanisms of autism spectrum disorder. [PDF]
, 2020 Early brain development is a critical epoch for the development of autism spectrum disorder (ASD). In vivo animal models have, until recently, been the principal tool used to study early brain development and the changes occurring in neurodevelopmental ...
Geschwind, Daniel H, Gordon, Aaron
core
SP8 Transcriptional Regulation of Cyclin D1 During Mouse Early Corticogenesis
Frontiers in Neuroscience, 2018 Multiple signals control the balance between proliferation and differentiation of neural progenitor cells during corticogenesis. A key point of this regulation is the control of G1 phase length, which is regulated by the Cyclin/Cdks complexes.
Ugo Borello +5 more
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Statistical models of complex brain networks: a maximum entropy approach [PDF]
arXiv, 2022 The brain is a highly complex system. Most of such complexity stems from the intermingled connections between its parts, which give rise to rich dynamics and to the emergence of high-level cognitive functions. Disentangling the underlying network structure is crucial to understand the brain functioning under both healthy and pathological conditions ...
arxiv
HORMESIS, CELL DEATH, AND REGENERATIVE MEDICINE FOR NEURODEGENERATIVE DISEASES [PDF]
, 2012 Although the adult human brain has a small number of neural stem cells, they are insufficient to repair the damaged brain to achieve significant functional recovery for neurodegenerative diseases and stroke.
Wang, Guanghu
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mdka Expression Is Associated with Quiescent Neural Stem Cells during Constitutive and Reactive Neurogenesis in the Adult Zebrafish Telencephalon [PDF]
, 2022 In contrast to mammals, adult zebrafish display an extraordinary capacity to heal injuries and repair damage in the central nervous system. Pivotal for the regenerative capacity of the zebrafish brain at adult stages is the precise control of neural stem
Lübke, Luisa +3 more
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Epigenetics & ChromatinPost-translational modifications of histone H3 on lysine 9, specifically acetylation (H3K9ac) and tri-methylation (H3K9me3), play a critical role in regulating chromatin accessibility.
Wilhelm Bouchereau +8 more
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Cell Reports, 2016 The molecular linkage between neocortical projection neuron subtype and area development, which enables the establishment of functional areas by projection neuron populations appropriate for specific sensory and motor functions, is poorly understood ...
Mollie B. Woodworth +5 more
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