Results 31 to 40 of about 447,656 (309)

The Oxygen and Glucose Deprivation of Immature Cells of the Nervous System Exerts Distinct Effects on Mitochondria, Mitophagy, and Autophagy, Depending on the Cells’ Differentiation Stage

open access: yesBrain Sciences, 2023
Perinatal brain damage, one of the most common causes of lifelong impairment, is predominantly caused by a lack of oxygen and glucose during early development.
Denis Jagečić   +4 more
doaj   +1 more source

NANOG Is Required for the Long-Term Establishment of Avian Somatic Reprogrammed Cells

open access: yesStem Cell Reports, 2018
Summary: Somatic reprogramming, which was first identified in rodents, remains poorly described in non-mammalian species. Here, we generated avian reprogrammed cells by reprogramming of chicken and duck primary embryonic fibroblasts.
Aurélie Fuet   +6 more
doaj   +1 more source

Development of nanoRibo-seq enables study of regulated translation by cortical neuron subtypes, showing uORF translation in synaptic-axonal genes

open access: yesCell Reports, 2023
Summary: Investigation of translation in rare cell types or subcellular contexts is challenging due to large input requirements for standard approaches. Here, we present “nanoRibo-seq” an optimized approach using 102- to 103-fold less input material than
John E. Froberg   +2 more
doaj   +1 more source

Brain-to-Brain Synchrony in the STEM Classroom [PDF]

open access: yesCBE—Life Sciences Education, 2020
Recent advances in portable electroencephalography (EEG) now allow researchers to collect brain data from groups of students in real-world classrooms. This Essay highlights how this emerging line of research can open new opportunities for collaboration between discipline-based education researchers and cognitive and social neuroscientists.
openaire   +2 more sources

Specific frontal neural dynamics contribute to decisions to check

open access: yesNature Communications, 2016
Information seeking is thought to rely on the brain's frontal cortex but which regions specifically control this drive remains unknown. Here the authors show that monkeys deciding to seek information on the current state of the environment showed ...
Frederic M. Stoll   +2 more
doaj   +1 more source

Extracellular vesicles derived from human ES-MSCs protect retinal ganglion cells and preserve retinal function in a rodent model of optic nerve injury

open access: yesStem Cell Research & Therapy, 2020
Background Retinal and/or optic nerve injury is one of the leading causes of blindness due to retinal ganglion cell (RGC) degeneration. There have been extensive efforts to suppress this neurodegeneration.
Seyedeh-Zahra Seyedrazizadeh   +8 more
doaj   +1 more source

Enhanced cultivation of chicken primordial germ cells

open access: yesScientific Reports, 2023
The cultivation and expansion of chicken primordial germ cells (cPGCs) are of critical importance for both biotechnological applications and the management of poultry genetic biodiversity.
Nima Dehdilani   +8 more
doaj   +1 more source

Stem Cells on the Brain [PDF]

open access: yesArchives of Neurology, 2008
Mutations that cause autosomal recessive primary microcephaly (MCPH), including MCPH1 through MCPH6, have provided insight into the normal programming that directs brain growth and defines ultimate brain size. The common denominator in these mutations is that they all manifest within neural stem and progenitor cells, decreasing their numbers at various
openaire   +2 more sources

TGF-beta signalling in the adult neurogenic niche promotes stem cell quiescence as well as generation of new neurons. [PDF]

open access: yes, 2014
Members of the transforming growth factor (TGF)-b family govern a wide range of mechanisms in brain development and in the adult, in particular neuronal/glial differentiation and survival, but also cell cycle regulation and neural stem cell maintenance ...
Strauss, O.   +27 more
core   +1 more source

NMDAR mediated dynamic changes in m6A inversely correlates with neuronal translation

open access: yesScientific Reports, 2022
Epitranscriptome modifications are crucial in translation regulation and essential for maintaining cellular homeostasis. N6 methyladenosine (m6A) is one of the most abundant and well-conserved epitranscriptome modifications, which is known to play a ...
Naveen Kumar Chandappa Gowda   +4 more
doaj   +1 more source

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