Results 11 to 20 of about 409,945 (260)

Anastasis in Glioblastoma, Brain Cancer Stem, and Brain Stem Cells

Journal of Basic and Clinical Health Sciences, 2021
Objective: Anastasis, a process that has been discovered recently, halts apoptosis, and thus, recovers the survival functions of cells. It may be suggested that anastasis is related to cancer progression, especially in cancer stem cells which are responsible for therapy resistance, metastasis, and recurrence.
Melodi INCEBOZ, Bakiye GOKER BAGCA, Ayşe CANER, Cumhur GÜNDÜZ   +3 more
openaire   +4 more sources

NMDAR mediated translation at the synapse is regulated by MOV10 and FMRP

Molecular Brain, 2019
Protein synthesis is crucial for maintaining synaptic plasticity and synaptic signalling. Here we have attempted to understand the role of RNA binding proteins, Fragile X Mental Retardation Protein (FMRP) and Moloney Leukemia Virus 10 (MOV10) protein in ...
Preeti Madhav Kute, Sarayu Ramakrishna, Nagammal Neelagandan, Sumantra Chattarji, Ravi. S. Muddashetty   +4 more
doaj   +1 more source

Radial Migration Dynamics Is Modulated in a Laminar and Area-Specific Manner During Primate Corticogenesis

Frontiers in Cell and Developmental Biology, 2020
The orderly radial migration of cortical neurons from their birthplace in the germinal zones to their final destination in the cortical plate is a prerequisite for the functional assembly of microcircuits in the neocortex.
Veronique Cortay, Delphine Delaunay, Dorothée Patti, Elodie Gautier, Nathalie Doerflinger, Pascale Giroud, Kenneth Knoblauch, Cyril Huissoud, Cyril Huissoud, Henry Kennedy, Henry Kennedy, Colette Dehay   +11 more
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Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns

Molecular Autism, 2020
Background Fragile X syndrome (FXS), a neurodevelopmental disorder, is a leading monogenetic cause of intellectual disability and autism spectrum disorder.
Shreya Das Sharma, Rakhi Pal, Bharath Kumar Reddy, Bhuvaneish T. Selvaraj, Nisha Raj, Krishna Kumar Samaga, Durga J. Srinivasan, Loren Ornelas, Dhruv Sareen, Matthew R. Livesey, Gary J. Bassell, Clive N. Svendsen, Peter C. Kind, Siddharthan Chandran, Sumantra Chattarji, David J. A. Wyllie   +15 more
doaj   +1 more source

The Oxygen and Glucose Deprivation of Immature Cells of the Nervous System Exerts Distinct Effects on Mitochondria, Mitophagy, and Autophagy, Depending on the Cells’ Differentiation Stage

Brain Sciences, 2023
Perinatal brain damage, one of the most common causes of lifelong impairment, is predominantly caused by a lack of oxygen and glucose during early development.
Denis Jagečić, Dražen Juraj Petrović, Iva Šimunić, Jasmina Isaković, Dinko Mitrečić   +4 more
doaj   +1 more source

NANOG Is Required for the Long-Term Establishment of Avian Somatic Reprogrammed Cells

Stem Cell Reports, 2018
Summary: Somatic reprogramming, which was first identified in rodents, remains poorly described in non-mammalian species. Here, we generated avian reprogrammed cells by reprogramming of chicken and duck primary embryonic fibroblasts.
Aurélie Fuet, Guillaume Montillet, Christian Jean, Pauline Aubel, Clémence Kress, Sylvie Rival-Gervier, Bertrand Pain   +6 more
doaj   +1 more source

Development of nanoRibo-seq enables study of regulated translation by cortical neuron subtypes, showing uORF translation in synaptic-axonal genes

Cell Reports, 2023
Summary: Investigation of translation in rare cell types or subcellular contexts is challenging due to large input requirements for standard approaches. Here, we present “nanoRibo-seq” an optimized approach using 102- to 103-fold less input material than
John E. Froberg, Omer Durak, Jeffrey D. Macklis   +2 more
doaj   +1 more source

Brain-to-Brain Synchrony in the STEM Classroom [PDF]

CBE—Life Sciences Education, 2020
Recent advances in portable electroencephalography (EEG) now allow researchers to collect brain data from groups of students in real-world classrooms. This Essay highlights how this emerging line of research can open new opportunities for collaboration between discipline-based education researchers and cognitive and social neuroscientists.
openaire   +2 more sources

Specific frontal neural dynamics contribute to decisions to check

Nature Communications, 2016
Information seeking is thought to rely on the brain's frontal cortex but which regions specifically control this drive remains unknown. Here the authors show that monkeys deciding to seek information on the current state of the environment showed ...
Frederic M. Stoll, Vincent Fontanier, Emmanuel Procyk   +2 more
doaj   +1 more source

Extracellular vesicles derived from human ES-MSCs protect retinal ganglion cells and preserve retinal function in a rodent model of optic nerve injury

Stem Cell Research & Therapy, 2020
Background Retinal and/or optic nerve injury is one of the leading causes of blindness due to retinal ganglion cell (RGC) degeneration. There have been extensive efforts to suppress this neurodegeneration.
Seyedeh-Zahra Seyedrazizadeh, Sara Poosti, Abdoreza Nazari, Mehdi Alikhani, Faezeh Shekari, Farzad Pakdel, Koorosh Shahpasand, Leila Satarian, Hossein Baharvand   +8 more
doaj   +1 more source