Results 41 to 50 of about 447,656 (309)

Notch promotes neural lineage entry by pluripotent embryonic stem cells [PDF]

, 2006
A central challenge in embryonic stem (ES) cell biology is to understand how to impose direction on primary lineage commitment. In basal culture conditions, the majority of ES cells convert asynchronously into neural cells.
Smith, Austin G, Austin G Smith, Heavey Barry, Alexandra Benchoua, Benchoua, Alexandra, Smith, Austin,, Benchoua Alexandra, Sally Lowell, Smith Austin G, Lowell, Sally; id_orcid, Smith, Austin, G., Lowell Sally, Lowell, Sally, Heavey, Barry, Barry Heavey   +14 more
core   +1 more source

Targeted transgenic RNAi knockdown of cell fate determinants induces neoplastic tumor growth and metastasis in a Drosophila transplantation model of neural stem cell derived cancer [PDF]

, 2012
Genetic models such as Drosophila have sophisticated transgenic and molecular genetic tools available to investigate proliferation control in normal and tumorigenic neural stem cells.
Reichert, Heinrich, Laurenson, Anne-Sophie, Saini, Nidhi, Jiang, Yanrui   +3 more
core   +1 more source

Neural stem cell biology and neurogenesis in mouse models of aging and Alzheimer's disease [PDF]

, 2006
The etiology of Alzheimer’s disease (AD) remains a great challenge for neurological research. Extensive investigations for almost one hundred years have led to profound insights of the pathological and molecular mechanisms that affect the AD brain, and
Ermini, Florian V.
core   +1 more source

Age correlation of cerebral corpus callosum and brainstem area indicators

Сибирский научный медицинский журнал, 2022
Since aging is characterized by morphofunctional changes in humans, longevity leads to an increase in age-associated features of their bodies. Aim of the study was to carry out a comparative analysis of the cerebral corpus callosum and brainstem area in ...
A. A. Balandin, G. S. Yurushbaeva, I. A. Balandina   +2 more
doaj   +1 more source

Regulation of boundary cap neural crest stem cell differentiation after transplantation [PDF]

, 2009
Success of cell replacement therapies for neurological disorders will depend largely on the optimization of strategies to enhance viability and control the developmental fate of stem cells after transplantation.
Hjerling-Leffler, J, Aldskogius, Hakan, Wegner, M, Hjerling-Leffler, Jens, Kozlova, Elena N, Medvinsky, Alexander, Berens, C, Aldskogius, H, Kozlova, EN, Berens, Christian, Kanaykina, Nadezda, Sandelin, Martin, Schreiner, S, Wegner, Michael, Kanaykina, N, Sandelin, M, Liakhovitskaia, A, Medvinsky, A, Liakhovitskaia, Anna, Schreiner, Silke   +19 more
core   +1 more source

Embryonic cortical neural stem cells migrate ventrally and persist as postnatal striatal stem cells [PDF]

, 2006
Embryonic cortical neural stem cells apparently have a transient existence, as they do not persist in the adult cortex. We sought to determine the fate of embryonic cortical stem cells by following Emx1(IREScre); LacZ/EGFP double-transgenic murine cells ...
Seaberg, R.M., Cindi M. Morshead, Morshead, C.M., Kevin R. Jones, Gorski, J.A., Raewyn M. Seaberg, Etienne Labbé, Jessica A. Gorski, Attisano, L., Jones, K.R., Sandrine Willaime-Morawek, Willaime-Morawek, S., Labbé, E., van der Kooy, D., Claudia Batista, Batista, C., Angela Kam, Liliana Attisano, Derek van der Kooy   +18 more
core   +1 more source

Morphological characteristics of lateral branches of human basilar artery [PDF]

Vojnosanitetski Pregled, 2018
Background/Aim. Lateral branches of basilar artery mostly supply pons and cerebellum. The aim of this study was to determine the morphological characteristics of lateral branches and side branches of the individual lateral branches of human basilar ...
Gajanin Vesna, Sladojević Igor, Šarović-Vukajlović Mirka, Gajanin Radoslav, Ninković-Baroš Đuka, Krivokuća Božo   +5 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Purification of Immature Neuronal Cells from Neural Stem Cell Progeny [PDF]

Large-scale proliferation and multi-lineage differentiation capabilities make neural stem cells (NSCs) a promising renewable source of cells for therapeutic applications.
Brent A Reynolds, اسفندياري, ابراهيم, Reynolds, Brent A, Maryam Rahman, Osborne, Geoffrey W, Dennis A Steindler, Adams, David J, Dennis A. Steindler, Takahiro Yasuda, Bjorn Scheffler, Brent A. Reynolds, Scheffler, Bjorn, Mohammad G Golmohammadi, گل محمدی, محمد قاسم, Geoffrey W Osborne, Hassan Azari, David J. Adams, Mohammad G. Golmohammadi, Deleyrolle, Loic P, Steindler, Dennis A, Ebrahim Esfandiari, Loic P Deleyrolle, آذری, حسن, Yasuda1, Takahiro, رحمان, مریم, David J Adams, Loic P. Deleyrolle, Geoffrey W. Osborne   +27 more
core   +1 more source

A multipotent transit-amplifying neuroblast lineage in the central brain gives rise to optic lobe glial cells in Drosophila [PDF]

, 2013
The neurons and glial cells of the Drosophila brain are generated by neural stem cell-like progenitors during two developmental phases, one short embryonic phase and one more prolonged postembryonic phase.
Reichert, Heinrich, Viktorin, Gudrun, Riebli, Nadia   +2 more
core   +1 more source