Results 51 to 60 of about 447,656 (309)

Acute brain stem vertigo without neurological deficits

BLDE University Journal of Health Sciences, 2021
An infarct at the brain stem or cerebellum is rarely associated with vertigo without any other localizing clinical features. Stroke at the posterior circulation of the brain may cause spontaneous vertigo and imbalance.
Santosh Kumar Swain
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Niche-independent symmetrical self-renewal of a mammalian tissue stem cell.

, 2005
Pluripotent mouse embryonic stem (ES) cells multiply in simple monoculture by symmetrical divisions. In vivo, however, stem cells are generally thought to depend on specialised cellular microenvironments and to undergo predominantly asymmetric divisions.
Luciano Conti, Thorsten Gorba (59561), Mauro Toselli, Biella, G, Sanzone Sveva, Toselli, M, Austin Smith, Reitano Erika, Reitano, E, T. Gorba, Smith Austin, Steven M Pollard, E. Reitano, Sveva Sanzone (59566), BIELLA, GERARDO ROSARIO, Smith A., Reitano E, Gorba T, Ying Ql, Ying Qi-Long, Conti, L, Conti L, Sun Y, Sanzone, S, L. Conti, S. Sanzone, Toselli Mauro, Steven M Pollard (59560), Qi-Long Ying (59567), Q. L. Ying, Cattaneo Elena, Pollard, S M, Luciano Conti (59559), Y. R. Sun, Pollard Sm, Cattaneo E, Sun, Y R, Sveva Sanzone, Smith, A, Erika Reitano, Pollard Steven M, Yirui Sun, TOSELLI, MAURO GIUSEPPE, Thorsten Gorba, Ying, Q L, Yirui Sun (59565), Ying, QL, Conti Luciano, Gerardo Biella, Sun Yirui, Elena Cattaneo, E. Cattaneo, Mauro Toselli (59563), Austin Smith (59569), Qi-Long Ying, Biella Gerardo, Erika Reitano (59562), Pollard, SM, Cattaneo, E, Sanzone S, G. Biella, Gerardo Biella (59564), Gorba Thorsten, Gorba, T, A. Smith, Elena Cattaneo (59568), Sun, Y, S. M. Pollard, M. Toselli   +68 more
core   +1 more source

Efficient generation of germline chimeras in a non-rodent species using rabbit induced pluripotent stem cells

Nature Communications
Pluripotent stem cells have long been used to produce knockout mice via germline chimera technology. However, aside from the rat, this approach has not been successfully applied to other mammals.
Hong-Thu Pham, Florence Perold, Yannicke Pijoff, Nathalie Doerflinger, Sylvie Rival-Gervier, Maëlle Givelet, Anaïs Moulin, Manon Ressaire, Emilie Da Silva Fernandes, Valeska Bidault, Luc Jouneau, Véronique Duranthon, Florence Wianny, Bertrand Pain, Ingrid Plotton, Thierry Joly, Marielle Afanassieff, Pierre Savatier, Nathalie Beaujean   +18 more
doaj   +1 more source

Astroglial Control of the Antidepressant-Like Effects of Prefrontal Cortex Deep Brain Stimulation

EBioMedicine, 2015
Although deep brain stimulation (DBS) shows promising efficacy as a therapy for intractable depression, the neurobiological bases underlying its therapeutic action remain largely unknown.
A. Etiévant, C. Oosterhof, C. Bétry, E. Abrial, M. Novo-Perez, R. Rovera, H. Scarna, C. Devader, J. Mazella, G. Wegener, C. Sánchez, O. Dkhissi-Benyahya, C. Gronfier, V. Coizet, J.M. Beaulieu, P. Blier, G. Lucas, N. Haddjeri   +17 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Cortex- and striatum-derived neural stem cells produce distinct progeny in the olfactory bulb and striatum [PDF]

, 2008
Neural stem cells can be isolated from the mouse embryonic cortex but do not persist in the adult cortex. In contrast, neural stem cells from the striatal embryonic germinal zone persist in the adult subependyma.
Willaime-Morawek, S., Van der Kooy, D.
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

ABC of Brain Stem Death: From Brain Death to Brain Stem Death

, 1982
In the second in a series of nine articles on brain death, a British neurologist traces the evolution of British and American criteria for establishing brain death, distinguishes between whole brain death and death of the brain stem, and describes the ...
Pallis, Christopher
core   +1 more source

FACS purification and transcriptome analysis of drosophila neural stem cells reveals a role for Klumpfuss in self-renewal [PDF]

, 2012
Drosophila neuroblasts (NBs) have emerged as a model for stem cell biology that is ideal for genetic analysis but is limited by the lack of cell-type-specific gene expression data.
Jonas Steinmann, Heinrich Reichert, Reichert, Heinrich, Maria Novatchkova, Burkard, Thomas R., Laurenson, Anne-Sophie, Anne-Sophie Laurenson, Knoblich, Juergen A., Steinmann, Jonas, van der Horst, Suzanne, Berger, Christian, Novatchkova, Maria, Christian Berger, Juergen A. Knoblich, Thomas R. Burkard, Heike Harzer, Suzanne van der Horst, Harzer, Heike   +17 more
core   +1 more source